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Database: UniProt
Entry: A0A087XJU3_POEFO
LinkDB: A0A087XJU3_POEFO
Original site: A0A087XJU3_POEFO 
ID   A0A087XJU3_POEFO        Unreviewed;      2426 AA.
AC   A0A087XJU3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   22-NOV-2017, entry version 15.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor, type 1b {ECO:0000313|Ensembl:ENSPFOP00000006046};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000006046, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Ensembl:ENSPFOP00000006046, ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Ensembl:ENSPFOP00000006046};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000006046}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSPFOP00000006046}.
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DR   EMBL; AYCK01010920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01010921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01010922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01010923; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPFOT00000006056; ENSPFOP00000006046; ENSPFOG00000004491.
DR   GeneTree; ENSGT00760000119152; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000493; InsP3_rcpt-bd.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 3.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50919; MIR; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028760};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1951   1973       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1985   2003       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2031   2049       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2069   2096       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2117   2139       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2247   2270       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       28     84       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2357   2405       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2426 AA;  276570 MW;  B1BF025E5D008376 CRC64;
     MYTLVPVPDG MEVSSIFELD PTTLRGGDSM VPRSSYVRLR HLCTNTWVHS TNLPIDKEEE
     KPVMLRIGTS AVKEDKEAFA IVPVPPSEVR DLDFANDASK VLASIAGKLE KGTITQNERR
     FVTKLLEDLV FFVVDIPNSG QDVLEIMVNK PNRERQKLMR EQNILKQIFK LLQAPFTDSG
     DGPMLRLEEL GDQRHAPFRH ICRLCYRVLR HSQQDYRKNQ EYIAKQFRFM QKQIGYDVLA
     EDTITALLHN NRKLLEKHIT AAEIDTFVTL VRKNREPRFL DYLSDLCVSM HKSIPVTQEL
     ICNAVLDSSN ADILIETKLV LSRFEIESTA NGEDPVEPEE VEEVWLFWKD NCKEVRSKSV
     RELAQDAKEG QKEDQEVVSY YRCQLNLFAR MCLDRQYLAI NKISGQLDVD LILRCMSDED
     LPFDLRASFC RLMLHMHVDR DPQEQVTPVK YARLWSEIPS KIAIDDYDND GTTRDEIKER
     FSLTMDFVET YLREVVSQNI PFSDKEKNKL TFEVVNLARN LIYFGFYNFS DLLRLTKILL
     NILDCVHVST VFPINKIEKG DESKGGSNVM KSIHGVGELM TQVVLRGGGL LPATPTHQPE
     GDVVKTQTEP EREDIMVMDT KLKIIEILQF ILNVRLDYRI SCLLCIFKRE FDESNPQGDN
     AVSANGGNNI TPQMPGNLDF ENIEEQAEGI FGGSEENTPL DLDDHGGRTF LRVLLHLTMH
     DYPPLVSGAL HLLFRHFSQR QEVLMAFKQV QLLVTSQDVE NYKQIKSDLD QLRSIVEKSE
     LWVYKRQGED GMDGDGPSES DSKKKGDSPG SDKKKSESTS SYNYRVVKEI LVRLSKLCVQ
     EGISGKKSKK QQQRLLRNMG AHSVVLELLQ IPYEKGEDVR MQDIMKLAHE FLQNFCAGNQ
     QNQTLLHKHI NLFLNPGILE AVTMQHIFMN NSQLCNEINE RVVQHFVHCT ETHGRHVQYL
     KFLQTIVKAD NKFIKKCQDI VMAELVNSGE DVLVFYNDRA SFQTLIQMMR SERERLDENS
     PLMYHIHLVE LLAVCTEGKN VYTEIKCNSL LPLDDIVRVV THEDCIPEVK IAYINFLNHC
     YVDTEVEMKE IYTSNHMWKL FENFLVDICR VCNNTSDRKH ADTILERYVT ETVMSIVTCF
     FSSPFSDQST SLQMARHMYT RQPVFVQLLQ GVFRVYHCNW LNPAQKHSVE GCIKVLSDVA
     KSRAIAIPVD LDSQVNNLFV KPNNVVQKTL LNWKQSAKNT SRRESSLCAS KDYRNIIEKL
     QDIVSALEDR LRPLVQAELS VLVDVLHRPE LLFPENTDAR KKCESGGFIS KLIKHTKQLL
     EENEERLCIK VLQTLREMMT KDRGYGVKLI AFDDEMDVAE LAPPPEPEVP AEELDPNQPL
     KQVEDQRRGE ALRLILVNRY YGNIKPGQRR ESLTSYSNGP LTPGAQGKSP TLVSAGIGGR
     GELSLAEVQC HLDKEGASDL VIDLIMNATS DRIFQESILL AIALLEGGNT VIQRSFYNRL
     TGDNKSEKFF KVFYERMKLA QQEIKATVTV NTSDLGSKKK DEEPPDKDMP TRKKVKDVPV
     VAMVTEEVKE QLVEASAVTK KAYATYRREA EAEEHQAAAA DGAPVPTTDK SQDEGEMSVI
     ITIMQPILRL MQLLCENHNR DLQNFLRNQN NKNNYNLVCE TLQFLDCICG STTGGLGLLG
     LYINEKNVGL INQTVESLTE YCQGPCHENQ NCIATHECNG IDIIIALILN DINPLGKKRM
     DLVLELKNNA SKLLLAIMES RHDSENAERI LYNMRPKELV EVIKKAYMQG EIEVEEPEEG
     EDGEEEHSAS PRNVGHNIYI LAHQLARHNK ELQAMLKPGG TYGEGDEALE FYAKHTAQIE
     IVRLDRTMEQ IVFPVPNICE FLTQESKLRV YYTTERDEQG SKINDFFLRS EDLFNEMNWQ
     KKLRGTQEAT GNTNTVPSQP ILYWCSRNMS FWSSISFNLA VLMNLLVAFF YPLEGVRGGT
     LEPHLSALLW MAMLVSLAIV IVLPQPHGIR ALIASTILRL IFSVGLEPTL LLLGGFNLCN
     KVIFLMSFVG NRGTFTRGYK AMIMDVEFLY HLLYLIICSL GVFVHVFFYS LLLFDLVYRE
     ETLLNVIKSV TRNGRSIVLT AVLALILVYL FSIVGYIFFK DDFILAVDRI PNKTLEHGAS
     MIGEFFSGGA CQKENGENCS TEAVMDAAVA VQPSVVIEDK ERTCDSLLMC IVTVLSHGLR
     SGGGVGDVLR KPSKEEPLFA ARVIYDLLFF FMVIIIVLNL IFGVIIDTFA DLRSEKQKKE
     EILKTTCFIC GLERDKFDNK TVTFEEHIKV EHNMWHYLFF IVLVKVKDST EFTGPESYVA
     EMIREHNLDW FPRMRAMSLV SSDADGEQNE IRNLQEKLES TMKLVTNLSG QLTELKEQMT
     EQRKQKQRIG LLGHPQHLNV NPQQPA
//
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