ID A0A087XLY0_POEFO Unreviewed; 1193 AA.
AC A0A087XLY0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Zinc finger, MYND-type containing 8 {ECO:0000313|Ensembl:ENSPFOP00000006783.2};
GN Name=ZMYND8 {ECO:0000313|Ensembl:ENSPFOP00000006783.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000006783.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000006783.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01009736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XLY0; -.
DR STRING; 48698.ENSPFOP00000006783; -.
DR Ensembl; ENSPFOT00000006795.2; ENSPFOP00000006783.2; ENSPFOG00000006444.2.
DR eggNOG; KOG1473; Eukaryota.
DR eggNOG; KOG3612; Eukaryota.
DR GeneTree; ENSGT00940000154897; -.
DR OMA; DEPEGDW; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd05508; Bromo_RACK7; 1.
DR CDD; cd15538; PHD_PRKCBP1; 1.
DR CDD; cd20160; PWWP_PRKCBP1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR044075; PRKCBP1_PHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR021931; ZMYND8.
DR InterPro; IPR037967; ZMYND8_Bromo_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR002893; Znf_MYND.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46453; PROTEIN KINASE C-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR46453:SF5; PROTEIN KINASE C-BINDING PROTEIN 1 ISOFORM X1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12064; DUF3544; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF00855; PWWP; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 124..169
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 201..271
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 313..363
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 1100..1134
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 910..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1137..1193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1030..1096
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..816
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1193 AA; 131156 MW; A382415CA93B9E34 CRC64;
SVIEEEGKTE NYTEAEEMEI STRSKGPNIA ARRGILRKHD LKTENAGSTE RLAQKRKIPS
PSNSSSGHSP AESSPCPVKK KKKPGAGSST KDQSELRHGP FYYAKQPALT TDPVDVVPQD
GRNDFYCWLC HREGQVLCCE LCPRVYHAKC LKLPAEPEGD WFCPECEKIT VAECIETQSK
AMMMLTTDQL SYLLKFALQK MKQPGTEPFQ KPVSLEQHPD YAEYIFHPMD LCTLEKNIKK
KMYGCTEAFL ADVKWILHNC IIYNGGNHKL TATAKVIVKI CEHEMNEIEV CPECYLSACQ
KRENWFCEPC SHPHPLVWAK LKGFPFWPAK ALRDKDGQVD ARFFGQHDRA WVPLNNCYLM
SKEIPFSVKK TKSIFNSAMQ EMEVYVENMR KKFGVFNYAP FRTPYTPDNS FQLLLDPSNP
SSTAVKPEKP EKIKLSIDMS TSPKITLTRA VLSGLGGSTT GQRRPLGDEQ RSPMSTNSSA
HGISDGEQET ADRTQTKSAN SQSSAGEEST DCTGTNTAAF CGFESFLSHT GNSLDSPKPP
HSQTPDTPKQ EKAPQTGSIL NLNLDRSKAE MDLKELSETV QQKQGAAPAL TSPKRQIKSR
FQLNLDKTIE SCKAQLGIDE ISVDVYKGVE HSDSEDSDKS DSSESEYATD EESKSKPGQD
SAPKREPQKE PTRSKAKEQP SVSQTERDKA DPLVPNTTDD SSVSISDGEA EQKTSTGLGK
ENPDMTETAL EAPVSKEKCQ VKLKEAKQTV PTEDSDSEKE LVIDLGEEQP GKEKKRSRKD
GNVKESTVGK SEGKALTTSG LPSSNSTGAS TSSGVSTQSL MALPVTMVTF TTSSPATVSH
SSVSSAATTP SSSSSVSAAP ALKKQRPLLP RETVPVVQRA VVWSPAAKFQ TSSQKWHMQK
VQRQQQTQQL VVAPQTQASS PQQSSQSSRY QTRQAAKTVQ QKDPSISTST PAGTLVPSSP
ASVTMVAPSG LGIPASSPAG TDVYIPTASA DVAADIAKYT NKIMDAIKGT MTEMYNDLSK
GSSGNTIGEI KRLRIEIEKL QWLHQQELSE MKHNLDAELT MAEMRQSLEQ ERERLMAEVK
KQMELEKQQA VDETKKKQWC ANCRKEAIFY CCWNTSYCDY PCQQAHWPEH MKSCTQSATA
PQQEPEAEPT AEVPNKGAGQ TSSGPNTLRD APVSASSDKD CDTEKSTENV AVT
//
