ID A0A087XRR2_POEFO Unreviewed; 431 AA.
AC A0A087XRR2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Sphingomyelin synthase-related protein 1-like {ECO:0000313|Ensembl:ENSPFOP00000008465.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000008465.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000008465.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC {ECO:0000256|ARBA:ARBA00005441}.
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DR EMBL; AYCK01002062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007546184.1; XM_007546122.2.
DR RefSeq; XP_007546185.1; XM_007546123.2.
DR RefSeq; XP_007546186.1; XM_007546124.2.
DR RefSeq; XP_016523924.1; XM_016668438.1.
DR AlphaFoldDB; A0A087XRR2; -.
DR STRING; 48698.ENSPFOP00000008465; -.
DR Ensembl; ENSPFOT00000008477.2; ENSPFOP00000008465.2; ENSPFOG00000008498.2.
DR GeneID; 103134058; -.
DR KEGG; pfor:103134058; -.
DR eggNOG; KOG3058; Eukaryota.
DR GeneTree; ENSGT00940000155540; -.
DR OMA; PRSWNLI; -.
DR OrthoDB; 1343173at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd09515; SAM_SGMS1-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR045221; Sphingomyelin_synth-like.
DR InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR PANTHER; PTHR21290:SF25; SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1; 1.
DR PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR Pfam; PF14360; PAP2_C; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..77
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 431 AA; 48662 MW; 460F0E61E0FFBBA2 CRC64;
MSESNGRVSA WSSSQVGQWL QDEGFGQYVD LLCTQHRIDG VSLLALTEAD LRGPPLGLTV
LGHIKRLSVA LRRLQRENKA ELEELGLWPP DANSAGLSLG APRAEWSCDG AERRGCNGGD
HLCNGMELRL RNGSSRGCAP GTALCQTHSN GRFRQPMVGR LDPEVWKTVI SSVYVFLVCG
LTSFVMVIVH ERVPDMRTYP PLPDIFLDSV PRIPWAFVMA EACGLILCYM FLLILLLHKH
RSILLRRLCS LMGTVFLLRC CTMFVTSLSV PGQHLKCSSL SYGDTWGKIQ RALAIWSGFG
MTLTGVQTCG DYMFSGHTVV ITMLNFFVTE YTPRNWNLIH TISWVLNLFG IFFILAAHEH
YSIDVFIAFY ITTRLFLYYH TLANTRAFQH SRRARIWFPM FSFFECNVNG PVPNQYHWPF
SKPAFMKTLI G
//
