ID A0A087XTL6_POEFO Unreviewed; 1482 AA.
AC A0A087XTL6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Neurexin-1a {ECO:0000313|Ensembl:ENSPFOP00000009119.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000009119.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000009119.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AYCK01009262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007562469.1; XM_007562407.2.
DR STRING; 48698.ENSPFOP00000009119; -.
DR Ensembl; ENSPFOT00000009131.2; ENSPFOP00000009119.2; ENSPFOG00000008208.2.
DR GeneID; 103145123; -.
DR KEGG; pfor:103145123; -.
DR CTD; 565531; -.
DR eggNOG; KOG3514; Eukaryota.
DR GeneTree; ENSGT00940000154292; -.
DR OrthoDB; 2999458at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR15036:SF51; NEUREXIN-1; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1482
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001833494"
FT TRANSMEM 1409..1429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..209
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 205..243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 266..456
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 463..657
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 661..698
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 703..876
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 890..1065
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1068..1105
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1109..1310
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1315..1344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1369..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1449..1482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1482 AA; 162442 MW; ECFFFF71CE2D06AF CRC64;
MSVMAVCVWA AAPLLFLGLC LCSVGGQAQG EVLEFGGVSS QWGRFPVWNA CCESVLSFSL
RTQSQEGLLL YLDDEGFCDF LELLLLHGHL RLRFSIFCAE PAELQSGVAV SDGRWHAVRV
KRDWRNTSLE VDGRLEGWAE VTTKRRDMTV FSHTYMGGLS ADLHSSPQRL TSPSVREHPA
FRGWITAVSI NGSLVALDSS EGVTVTTGCG PDLQCQNGGV CSVVNDQAVC NCSDTGYQGN
DCSEEHSYTP GLAHLMIGDQ AREEYVATFK GSEYFCYDLS PNPIQSSSDE ITLSFKTLQR
NGLMLHTGKS ADYVNLALKN GAVSLVINLG SGAFEALVEP VNGKFNDNAW HDVKVTRNLR
QHSGIGHAMV TISVDGILTT TGYTQEDYTM LGSDDFFYVG GSPSTADLPG SPVSNNFMGC
LKEVVYKNND VRLELSRLAK QGDPKMKVSG VVSFKCESVA TLDPVTFDTP ESFVALSKWM
AKKAGSISFD FRTTEPNGLM LFSHGKPRQQ QRKDPRTPPT VKVDFFAIEM LDGHLYLLLD
MGSGTTKTKA IDRKVNDGEW YHVDFQRDGR SGTISVNSVR TAYTAPGDSE ILDLDDTLYL
GGLPEDRAGL IFPTEVWTAL LNYGYVGCIR DLFVDGQSKD IRRLAEAQRA VGVKPSCSRE
LPKQCLSNPC QHNGNCREGW NRYVCDCSGT GYLGRSCERD ATILSYDGSK FMKVQLPVAM
HTEAEDVSLR FRSQRAYGIL MATTSRNSAD TLRLELDGGR VRLTVNLDCI RINCTASKGP
ETIFAGSGLN DNEWHTVRVV RRGKSLKLTV DDLQTVEGQM AGDHTQLEFH NVETGIVTEK
RFMPIVPSNF IGHLQGLTLN GMSYIDLCKN GDIDYCELNA VIGYKSIVAD PITFRSRSSF
VTLPTLQAYY AMHLFMQFKT TSPDGLILFN RGDGNDFIVI ELVKGYLHYI SDLGNGAHLI
KGNSNSPLND NHWHNVHISR DTNNLHTVKI DTKVTTQTTM GAKNLDLKGD LYIGGVTKEM
YRELPKLVHS REGFQGCLAT LDLNGRLPDL LADALTTMGQ VERGCEGPST TCQEDSCSNQ
GVCLQQWEGF TCDCSMTSYA GPLCNDAGTT YIFGRDGGVV IYTWPPNERP STRADRLALG
FSTQQKHAIL LRVDSASGLG DYLQLQIDKG NIRVVFNVGT DDINIEESSK FVNDGKYHVV
RFTRSGGNAT LQLDDLPVIE RYPSGNNDNE RLAIARQRIP YRLGRVVDDW LLDKGRQLTI
FNSQTTVRVG GGEQGSAMFQ GQLSGLYYNG LRILNMAAEG HPHIRVEGSA RLVGDMPSSS
ITPQSSAAAG GNRSDSAPSI SDITTTTATN KKQVVTQTVD DLLVASAECP SDDEDIDPCD
SSARPPPPDV KVFPGPSEVV RESSSTTGMV VGIVAAAALC ILILLYAMYK YRNRDEGSYH
VDESRNYISN SATQPNGSAK DKPLGIAKIS KNKKNKDKEY YV
//
