ID A0A087XVX8_POEFO Unreviewed; 377 AA.
AC A0A087XVX8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Arf-GAP with dual PH domain-containing protein 1-like {ECO:0000313|Ensembl:ENSPFOP00000009931.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000009931.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000009931.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01006539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007556433.1; XM_007556371.2.
DR AlphaFoldDB; A0A087XVX8; -.
DR STRING; 48698.ENSPFOP00000009931; -.
DR Ensembl; ENSPFOT00000009946.2; ENSPFOP00000009931.2; ENSPFOG00000009639.2.
DR GeneID; 103140988; -.
DR KEGG; pfor:103140988; -.
DR eggNOG; KOG0703; Eukaryota.
DR GeneTree; ENSGT00940000155698; -.
DR OMA; DHEMIRQ; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:1902936; F:phosphatidylinositol bisphosphate binding; IEA:InterPro.
DR CDD; cd08832; ArfGap_ADAP; 1.
DR CDD; cd13252; PH1_ADAP; 1.
DR CDD; cd01251; PH2_ADAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR037849; PH1_ADAP.
DR InterPro; IPR037851; PH2_ADAP.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46021:SF5; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46021; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 9..129
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 132..233
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 255..359
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 377 AA; 43749 MW; 08AD194A1416B197 CRC64;
MSSDQERIRE RIKELLRKPG NGNCADCEVA DPEWASYTLG VFVCHSCSGL HRNIAQISKV
KSLLLDPWSY SELEFIDSVG NNAAKAKYEQ IVPAFYYRPT SKDCMLLRDQ WIRAKYERKE
FMCVERQEPY SAGYREGSLW KRGRDNGQYL SRKFILTERE GVLKYFNKHD AREPKAIMKL
STVNATFQPS KTGISHGLQI TYLKDNSTRN IFVYHEDGKE IVDWFNAIRG ARYHYLQVAF
PGAPNSELLP KLTRNYIKEG YMEKTGPKHT EGFKKRWFTM DDRRLMYFKD PLDAYARGEV
FIGSKENSYT VLPGLPANVQ GTHWPFGITI VTPDRKFLFA CETAEDQKAW MAAFQIVISR
PMLPQEYAVE AYFKHKP
//
