ID A0A087Y637_POEFO Unreviewed; 493 AA.
AC A0A087Y637;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Regulator of G-protein signaling 6-like {ECO:0000313|Ensembl:ENSPFOP00000013490.2};
GN Name=RGS6 {ECO:0000313|Ensembl:ENSPFOP00000013490.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000013490.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000013490.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01003415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01003416; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007549308.1; XM_007549246.2.
DR AlphaFoldDB; A0A087Y637; -.
DR STRING; 48698.ENSPFOP00000013490; -.
DR Ensembl; ENSPFOT00000013509.2; ENSPFOP00000013490.2; ENSPFOG00000013265.2.
DR GeneID; 103136135; -.
DR KEGG; pfor:103136135; -.
DR eggNOG; KOG3589; Eukaryota.
DR GeneTree; ENSGT00940000157159; -.
DR OMA; PWINDTV; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF2; REGULATOR OF G-PROTEIN SIGNALING 6; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 40..115
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 262..321
FT /note="G protein gamma"
FT /evidence="ECO:0000259|PROSITE:PS50058"
FT DOMAIN 337..452
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 56793 MW; 8450E381460984B3 CRC64;
MAEGSKDQGA TGAAEPEEDS PNMIVYRKME DIVTRIQDEK AGGVAIRTVK SFLSKIPSVV
SGADIVQWLM KNLSIEDPAE AIHLGSLIAA HGYIFPISDH VLTLKDDGTH YRFQSPYFWP
SNCWEPENTD YAIYLCKRTM QNKARLELAD YEAENLARLQ RAFARKWEFI FMQAEAQVKI
DRKKDKAERK ILDSQERAFW DVHRPVPGCV NTTEMDIRKC RREKNPHRVK KSVYGVPDDG
QSQPSPIHIS SQPSRKPTKE DVQKEITFLN IQLDRHCMKV SKVADSLMTY TEQFMEYDPF
VSGVEPSNPW ISDDATFWDM EASRDPSQQR VKKWGFSLEE ALKDPAGRDQ FLKFLESEFS
SENLRFWLAV QDLKRRPLQE VSTRAQEIWQ EFLAEGAPSS INLDSHSYER TSQNLKDPGR
YSYEDAQEHI FKLMKSDSYA RFLRSNIYQD LLSARKKQPA DTEQGRRTSL EKFTRSVGKS
LTGKRLTGLM QSS
//
