ID A0A087YDA5_POEFO Unreviewed; 1048 AA.
AC A0A087YDA5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Leucine rich repeats and immunoglobulin like domains 2 {ECO:0000313|Ensembl:ENSPFOP00000016008.2};
GN Name=LRIG2 {ECO:0000313|Ensembl:ENSPFOP00000016008.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000016008.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000016008.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01002394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007547021.1; XM_007546959.2.
DR AlphaFoldDB; A0A087YDA5; -.
DR STRING; 48698.ENSPFOP00000016008; -.
DR Ensembl; ENSPFOT00000016030.2; ENSPFOP00000016008.2; ENSPFOG00000015867.2.
DR GeneID; 103134630; -.
DR KEGG; pfor:103134630; -.
DR CTD; 9860; -.
DR eggNOG; KOG4194; Eukaryota.
DR GeneTree; ENSGT00940000158791; -.
DR OMA; QVTMNHN; -.
DR OrthoDB; 5405965at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05763; IgI_LRIG1-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF13855; LRR_8; 4.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1048
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001834337"
FT TRANSMEM 757..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 459..555
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 560..649
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 654..742
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 812..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1022..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 115268 MW; 757645AE801F49E4 CRC64;
MAEGWPTLPA LVVLLLSFSA WVTDSCPAPC SCPKGQDEVH ILECNRKRLS AAPLDVPDGI
TQVTMNHNDL AVFPFLGNVS SNITSLSLVH NRISELLMHE LQPYISLETL DLTSNSISVL
KVGAFPSIQL KYLNLSNNKI SLLEPGCFEN ISSSLLVLRL NRNRLVTLPS KVFKLPQLQL
LEMKRNKIKI VDSLTFKGLD SLKSLKMQRN GITKLMDGAF FGLNNIEELE LEHNNLTEVN
KVWLYGLRML RILQISHNAI GVIRPDAWEF CQKLEELDLS HNHLTRLEES AFVGLGFLET
LNLGENSISH LGEGVFSGLA HLRTLDIHNN EISWAIEDSI AVFDGMKKLN TLNLQRNKIK
SITQKAFEGL DELKELDLGK NGIMSIHPEA LSHLKLEVFV LNSSSLLCDC HMQWLGPWLK
ESQFLQSVSA VCAHPAGLLG RSILSISPDE FVCDDFPKPR ITTHPETSVA LRGNNMTLSC
VASSSSDSPM TTAWRKDGEV LYDAEVENYA RYQDGQLIYT TVLHLLNVNF TDEGLYQCVV
SNHFGSNYSN RAMLTINEMP SFLKTPMDLT IRTGMTARLE CAAEGHPSPQ IAWQKDGGTD
FPAARERRMH VMPDDDIFFI AKVKTEDMGV YSCTAQNAAG SLSANATLTV LETPSFVRDL
EDRTVARGET AVLQCIAGGS PAPRLNWTKD DGPLMLTERH FFAAANQLLI IVDAGPADAG
KYTCIMSNTV GTKRGHIYLS VSPLPSCDTA AGYDYDGWTT VGIVVIVVVC CVVGTSLVWV
IVIYHMRRKN EDYSITNTDE MNLPADIPSY LSSQGTLSEP QEGYSNSEAG SHQQLMPPLS
NGYIHKGTDG VCYGDTGSEV ETEGNGMLHC KMGSLFTGRS SFHPGESREG LAGVSSGGAG
PLVICSDCYD NANIYSRTRE YCQYAYLGED DSLDRALPSL KDGLGDAAHP EDTALDSLMH
SNHTSAEQYV KDSLSRSLWR EDEDPSSVSQ PGASHLSAAL HRTPALTSAA DRAAEQSEAV
ANYFPRQPTQ DHRSAYNRTN PQDHRAPT
//
