ID A0A087YJG9_POEFO Unreviewed; 374 AA.
AC A0A087YJG9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like {ECO:0000313|Ensembl:ENSPFOP00000018172.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000018172.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000018172.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219, ECO:0000256|RuleBase:RU004475}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYCK01014760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087YJG9; -.
DR STRING; 48698.ENSPFOP00000018172; -.
DR Ensembl; ENSPFOT00000018194.2; ENSPFOP00000018172.2; ENSPFOG00000018082.2.
DR eggNOG; KOG1430; Eukaryota.
DR GeneTree; ENSGT00940000155444; -.
DR OrthoDB; 3675908at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 9..291
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 374 AA; 42209 MW; CAED524220EEAA45 CRC64;
MSLRGDVCVV TGACGFLGKR LVRLLLEEEK ASEIRLLDRD VQTQVLESLE DCRGETTLSV
FEGDIRDGDF LRKALRGAST VFHIASLIDV TESMEYSEMY GVNVKGTQLL LEACIQENVV
SFIYTSTVEV MGPNPRGEPI INGTEDTVYN TTLKFNYSKT KKEAEDRTLQ ADGETLQNGG
RLSTCALRPT YIYGDGCRFL LGHMGDGIRN KNVLFRMSVP EAHVNPVYVG NVAFAHLQAA
RSLKDPQKRN AVGGRFYYLS DDTPPMSYSD FNHVLMSPLG FSIQDKLVLP LRLFYILCFL
LEALCTILRP FVRIVPPMNR QLLTLLNTSF TFSYEKAKED LGYVPRYSWD EARRRTTEWL
ASQLPAEREK IMSS
//
