ID A0A087YLC4_POEFO Unreviewed; 858 AA.
AC A0A087YLC4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Trafficking protein, kinesin binding 1a {ECO:0000313|Ensembl:ENSPFOP00000018827.1};
GN Name=TRAK1 {ECO:0000313|Ensembl:ENSPFOP00000018827.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000018827.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000018827.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the milton family.
CC {ECO:0000256|ARBA:ARBA00007007}.
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DR EMBL; AYCK01000082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087YLC4; -.
DR STRING; 48698.ENSPFOP00000018827; -.
DR Ensembl; ENSPFOT00000018849.1; ENSPFOP00000018827.1; ENSPFOG00000018712.1.
DR eggNOG; KOG4360; Eukaryota.
DR GeneTree; ENSGT00940000155697; -.
DR OMA; LACHEEH; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.287.1490; -; 1.
DR InterPro; IPR006933; HAP1_N.
DR InterPro; IPR022154; TRAK1/2_C.
DR PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR15751:SF11; TRAFFICKING KINESIN-BINDING PROTEIN 1; 1.
DR Pfam; PF04849; HAP1_N; 1.
DR Pfam; PF12448; Milton; 1.
DR SMART; SM01424; HAP1_N; 1.
DR SMART; SM01423; Milton; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 1..258
FT /note="HAP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01424"
FT DOMAIN 320..493
FT /note="Trafficking kinesin-binding protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01423"
FT REGION 87..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 17..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 115..258
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 320..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 93922 MW; 4536862EA63C9110 CRC64;
VLCADRVGQM TKTYSDIDAV TRLLEEKERD LELAARIGQS LLKKNKALSD RNDLLEDQVE
HIREEVSQLR HDLSMKDELL QFYTNAAEES EGESNTSTPV RLSEPSLSTP TLFPLDSLQK
KLKDLEEENK SLRSAANHLE TETISYEEKE QQLVNDCVKE LRAANLQISS LAEDLARKSE
DASRQQEEIT HLLSQIVDLQ KKAKLYAVEN EELTQHLGAA KDAQRQLTAE LRELQDKYAE
CMEILHEAQE ELKNLRNKSL PLSTPRRFHT LGLFPMDSLA AEIEGTMRKE LQMDDPDVEE
QRLHPKRVFQ TVKNLNLMRQ QRSSAAPSPL NIPGSNQNSC FTSSRSSRAG TPRSNSIYGS
ETGSGIILDN RTSSILEGPD DGSEDSNKRP PGTPGTPGSR DLEAALRRLS LRRDNYLSEK
RFFEEERERK LAYLGKEEEK GEADGSGDPG TPTESLLSFC SHPSFGSIWS GYSITARSYL
PEKLQIVKPL EGSATLHAWQ QLAQPHMGAL LDHRPGVVTK GFRTLEQDRE QEQEDSWQLD
QPEEDEASCD PFTGSSGESP APTGGQLSTI HFPGKCLSHT SSTYTFTTCR ILHPSDQLTS
VSPSQSGSAI GTPTHTSSPV PFSAPHTPSY TPCCTPRRLS LSLSLSESST NLRDSTKTTS
TSLGLVRLLL ERGISASVYD PCSWDRGLGA SGASTPTGSV QPCSPPCSPP QESASAATAR
PAFQFSPSKE DPPYYDAFLA SKPARTILRE VLMDLEREYD GEADEDGQNE VANLGLVDKL
KRFRTLSAVS ASVSSGSGLL APFSSSGLGG GLPGLNAGLR RNRSYPAMVG ASMAMKDPGG
PPCALIPQTM QTSQPQGP
//
