GenomeNet

Database: UniProt
Entry: A0A089X977_STRGA
LinkDB: A0A089X977_STRGA
Original site: A0A089X977_STRGA 
ID   A0A089X977_STRGA        Unreviewed;      1266 AA.
AC   A0A089X977;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   28-MAR-2018, entry version 18.
DE   SubName: Full=Multifunctional 2-oxoglutarate metabolism enzyme {ECO:0000313|EMBL:AIS00498.1};
DE            EC=2.2.1.5 {ECO:0000313|EMBL:AIS00498.1};
GN   Name=kgd {ECO:0000313|EMBL:AIS00498.1};
GN   ORFNames=SGLAU_22740 {ECO:0000313|EMBL:AIS00498.1};
OS   Streptomyces glaucescens.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1907 {ECO:0000313|EMBL:AIS00498.1, ECO:0000313|Proteomes:UP000029482};
RN   [1] {ECO:0000313|Proteomes:UP000029482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40922 / GLA.O {ECO:0000313|Proteomes:UP000029482};
RX   PubMed=25499805; DOI=10.1016/j.jbiotec.2014.11.036;
RA   Ortseifen V., Winkler A., Albersmeier A., Wendler S., Puhler A.,
RA   Kalinowski J., Ruckert C.;
RT   "Complete genome sequence of the actinobacterium Streptomyces
RT   glaucescens GLA.O (DSM 40922) consisting of a linear chromosome and
RT   one linear plasmid.";
RL   J. Biotechnol. 194:81-83(2015).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP009438; AIS00498.1; -; Genomic_DNA.
DR   RefSeq; WP_043504072.1; NZ_CP009438.1.
DR   EnsemblBacteria; AIS00498; AIS00498; SGLAU_22740.
DR   GeneID; 33992422; -.
DR   KEGG; sgu:SGLAU_22740; -.
DR   KO; K00164; -.
DR   Proteomes; UP000029482; Chromosome.
DR   GO; GO:0050439; F:2-hydroxy-3-oxoadipate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 3.30.559.10; -; 1.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029482};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029482};
KW   Transferase {ECO:0000313|EMBL:AIS00498.1}.
FT   DOMAIN      918   1111       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
FT   COILED      829    856       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1266 AA;  138734 MW;  CF97A1F757B88837 CRC64;
     MSPQSPSNAS SISTDADQAG KNPAAAFGAN EWLVDEIYQQ YLQDPNSVDR AWWDFFADYK
     PGAAGAPAPA GPAAAGAAET TPQTPTPAPQ PAAPAAPAQP AAPAAPAAPA PAAKAAAPSP
     AKPAQPAQAP ARPKAKAAPA AEAPEGPELV TLRGPAAAVA KNMNASLELP TATSVRAVPV
     KLLFDNRIVI NNHLKRARGG KISFTHLIGF AMVQAIKAMP SMNWSFGEKD GKPTLVKPPH
     INLGLAIDLV KPNGDRQLVV AAIKKAETLN FFEFWQAYED IVRRAREGKL TMDDFTGVTV
     SLTNPGGLGT VHSVPRLMPG QSVIMGVGSM DYPAEFQGTS QDTLNKLGIS KVMTLTSTYD
     HRVIQGAASG EFLRTVANLL LGENNFYDDI FEALRIPYEP VRWLKDIDAS HDDDVTKAAR
     VFELIHSYRV RGHVMADTDP LEYRQRKHPD LDIVEHGLTL WDLEREFAVG GFAGKSMMKL
     RDILGVLRDS YCRTTGIEFM HIQDPKQRKW IQDRVERPHA KPEREEQLRI LRRLNAAEAF
     ETFLQTKYVG QKRFSLEGGE SVIPLLDAVL DSAAESRLDE VVIGMAHRGR LNVLANIVGK
     SYAQIFREFE GNLDPKSMHG SGDVKYHLGA EGTFTGLDGE QIKVSLVANP SHLEAVDPVL
     EGVARAKQDI INKGGTDFTV LPVAIHGDAA FAGQGVVAET LNMSQLRGYR TGGTVHIVIN
     NQVGFTAAPE SSRSSMYATD VARMIEAPIF HVNGDDPEAV VRVARLAFEF RQAFNKDVVI
     DLICYRRRGH NESDNPAFTQ PLMYDLIDKK RSVRKLYTES LIGRGDITLE EAEQALQDYQ
     GQLEKVFTEV REATSQPSAV ETPDPQAEFP VAVGTAVTAE VVKRIAESQV NIPDHITVHP
     RLLPQLQRRA AMVEDGTIDW GMGETLAIGS LLLEGVPVRL AGQDSQRGTF GQRHAVIIDR
     ETGEEYTPLQ YLAEEQARLN VYNSLLSEYA AMGFEYGYSL ARPDALVMWE AQFGDFVNGA
     QTVVDEFISS AEQKWNQTSG VVLLLPHGYE GQGPDHSSAR PERFLQLCAQ NNMTVAMPTL
     PSNYFHLLRW QVHNPHHKPL VVFTPKSMLR LKAAASKAEE FTTGQFRPVI GDSSVDPAAV
     KKVVFCAGKV YYDLEAERVK RGVKDTAIIR IERLYPLPGA ELQAEIKKYP NAEKYLWAQE
     EPANQGAWPF IALNLIDHLD LAVGADVPHG ERLRRISRPH SSSPAVGSAK RHQAEQEQLV
     REVFEA
//
DBGET integrated database retrieval system