ID A0A089YN19_9PSED Unreviewed; 395 AA.
AC A0A089YN19;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AIS17813.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:AIS17813.1};
GN ORFNames=LT40_10600 {ECO:0000313|EMBL:AIS17813.1};
OS Pseudomonas rhizosphaerae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216142 {ECO:0000313|EMBL:AIS17813.1, ECO:0000313|Proteomes:UP000029499};
RN [1] {ECO:0000313|EMBL:AIS17813.1, ECO:0000313|Proteomes:UP000029499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16299 {ECO:0000313|EMBL:AIS17813.1};
RX PubMed=25483321; DOI=10.1016/j.jbiotec.2014.11.031;
RA Kwak Y., Jung B.K., Shin J.H.;
RT "Complete genome sequence of Pseudomonas rhizosphaerae IH5T (=DSM 16299T),
RT a phosphate-solubilizing rhizobacterium for bacterial biofertilizer.";
RL J. Biotechnol. 193:137-138(2015).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP009533; AIS17813.1; -; Genomic_DNA.
DR RefSeq; WP_043189687.1; NZ_CP009533.1.
DR AlphaFoldDB; A0A089YN19; -.
DR STRING; 216142.LT40_10600; -.
DR KEGG; prh:LT40_10600; -.
DR eggNOG; COG0183; Bacteria.
DR HOGENOM; CLU_031026_0_1_6; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000029499; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF138; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:AIS17813.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029499};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AIS17813.1}.
FT DOMAIN 6..264
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 272..392
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 350
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 380
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 395 AA; 40919 MW; F87E24BDA4849F3D CRC64;
MNEDPIVIVS AVRTPMGGFQ GDLRSLTAPQ LGAAAIAAAV ERAGVEAGSV DQVLFGCVLP
AGLGQAPARQ AALGAGLPYA TTCTTLNKMC GSGMQAMLMG HDALLAGSAR VVVAGGMESM
SNAPYLLDRA RDGYRMGHGR VLDHMFLDGL EDAYEPGRLM GTFAEDCAQG HGFSRQTQDE
FALASLSRAR QAISDGSFTS QIVPVQVTRN KQTLTISDDE QPPKANPDKI PTLKPAFREG
GTVTAANSSS ISDGAAALLL MRRSEAQARG LAPLAVIHGH TAFADAPHLF PVAPIGAIRK
LVETTGWALP DVDLFEINEA FAVVTLAAMQ ALDLPADKVN VNGGACALGH PIGASGARIV
VTLLAALRQR NLRRGIAAIC IGGGEATAIA VECLY
//
