ID   A0A090BU51_9GAMM        Unreviewed;       764 AA.
AC   A0A090BU51;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:BAP54496.1};
GN   ORFNames=THII_0199 {ECO:0000313|EMBL:BAP54496.1};
OS   Thioploca ingrica.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Thiotrichaceae; Thioploca.
OX   NCBI_TaxID=40754 {ECO:0000313|EMBL:BAP54496.1, ECO:0000313|Proteomes:UP000031623};
RN   [1] {ECO:0000313|EMBL:BAP54496.1, ECO:0000313|Proteomes:UP000031623}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kojima H., Ogura Y., Yamamoto N., Togashi T., Mori H., Watanabe T.,
RA   Nemoto F., Kurokawa K., Hayashi T., Fukui M.;
RT   "Ecophysiology of Thioploca ingrica as revealed by the complete genome
RT   sequence supplemented with proteomic evidence.";
RL   ISME J. 0:0-0(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; AP014633; BAP54496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090BU51; -.
DR   STRING; 40754.THII_0199; -.
DR   KEGG; tig:THII_0199; -.
DR   HOGENOM; CLU_010363_3_0_6; -.
DR   OrthoDB; 9761531at2; -.
DR   Proteomes; UP000031623; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR004797; Competence_ComEC/Rec2.
DR   InterPro; IPR025405; DUF4131.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF13567; DUF4131; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031623};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        234..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        297..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        405..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..485
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          520..708
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   764 AA;  85973 MW;  A7491E246077A526 CRC64;
     MRFNTLAFLV GIVYGQTWSH LPDPRWTILL LPVVLIAWKR PSLRLLCFGA LGLGWTVWRA
     NMILAQNLPR DLESKDLKLT GVVVNIPIKK AYGWQFDFGP NPTQEWPNPG RLRLQWYEQP
     LEPLIPGQHW QLTVRLKPTQ SLLNPGGFDY SSWLFQQQIR ATGYVSLRSQ PQLLQQPASL
     LNIDHWRYQL AKAIQQQLHH SPTQGIIIGL VIGEAQWITP RQQTVFKQTG TTHLIVISGS
     HISLVALLVF EITLRFWRYL GKPTLWLPAP YFAAVWGLLA AGFYALLAGF MVPTQRALIM
     LVVALSGILF TRRVMPSSIL AFSLLIVLLW DPLAVLSLGF WLSFGAVAVI VYVLTNRREL
     KTSVLLKWGL DSWRTQIAVS LLVAIIFLAQ FGYTPLSSLV ANSIAIPWFG LVIVPLALFG
     AALVKLLPII GGSALQLADY FMDALWVSLE WLANPHWMWY QAIPPWWAIV SALVGMLVLL
     LPRGFPAKWI GIIWLLPLFL TRTPYPQRGE VWFTLLDVGQ GLAAVIRTQN YTLVYDTGAK
     WNDNSDIGQT VVVPFLRTQG IREIDKLLIS HGDNDHIGGA QSLLKNLTVT EVITSVPEKF
     TQTNPVRLCQ AGQYWRWDDV DFKILHPPAH YLANGNSRSC VLKIITAGGS LLLPGDIETA
     AESDLLNHAY SDLAADILIV PHHGSQTSST EAFIQAVKPK IALFSVAYKN RFRLPNPEIV
     QRYHRYGIKT WTTASVGAIQ FRLSASGISQ PQLEKIARHR YWYD
//