ID A0A090LEA2_STRRB Unreviewed; 2656 AA.
AC A0A090LEA2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Short stop {ECO:0000313|EMBL:CEF68106.1, ECO:0000313|WBParaSite:SRAE_2000276400.1};
GN ORFNames=SRAE_2000276400 {ECO:0000313|EMBL:CEF68106.1,
GN ECO:0000313|WBParaSite:SRAE_2000276400.1,
GN ECO:0000313|WormBase:SRAE_2000276400};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF68106.1};
RN [1] {ECO:0000313|EMBL:CEF68106.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000276400.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF68106.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000276400.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; LN609529; CEF68106.1; -; Genomic_DNA.
DR STRING; 34506.A0A090LEA2; -.
DR EnsemblMetazoa; SRAE_2000276400.1; SRAE_2000276400.1; WBGene00262978.
DR WBParaSite; SRAE_2000276400.1; SRAE_2000276400.1; WBGene00262978.
DR WormBase; SRAE_2000276400; SRP00079; WBGene00262978; -.
DR eggNOG; KOG0516; Eukaryota.
DR OMA; PDENFKM; -.
DR OrthoDB; 5489926at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00176; SPEC; 7.
DR Gene3D; 1.20.58.60; -; 11.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF23; SHORT STOP, ISOFORM H; 1.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00435; Spectrin; 6.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00150; SPEC; 15.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 13.
DR PROSITE; PS51460; GAR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682}.
FT DOMAIN 2412..2489
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 1690..1715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2518..2551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2590..2656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 68..95
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 405..445
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 501..528
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 900..953
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1692..1710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2518..2538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2590..2626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2656 AA; 306640 MW; CB77CB77C3C2A1A3 CRC64;
MSDLVYNNQS TEKNVIEDIP FDNQLASNRI KIIREYLSKY EKEISKDLTE TDKLINEGTE
MEIPKEELEI LKNNKEKIKE AVNKLQNEEK IMSTKITDTK ENEKIIDEWK NKRDILVAFI
NENNKQLNII KDNSTSNDTV QSYLSEINNI EIDKASKKPL YEDTKKTLSL LKRTVSIPEI
SALKNEQQQL DDMWLDLSEN LQNTKNFCID TSNFFNDSEA LKKWLGDKNQ LLNTIGRLSA
DSNYIEHQIA LLERLKEECD DRKKSFNELN DLASHLLQNS SNDKYIDIIT TKKNDINEQW
NLLQLKLNQI KDNLINCNKL CQDFKNIQTN IKDQLLDTEK QIDCVTFSLI ENPTDLEEIF
YQVDDICIQG ANIVEPLITD SENLLQQLTK MSNDQDIWKV LNDDLNSSKD RVDKLIEKVQ
NIKNLSNISK NATLLNEKIN EMLKNPIINQ PISNDIISLK NQQKELSNFR NNELKGINDE
MSKVTESCKG MLKLPDKTLP CDNLEKLIEN IQNSWQKLNQ QIENKDREIS AKIQSIGNYD
DAFRSLCNWL EETEELIMNQ YKPSADTKVL RAELQNHNFQ MKMIEDKQQN IEGFLKLINK
LVDETTDENE KEELHEKADM IDSRYRDLVD SCNSRRVALQ DALMYSINWT SKTNELKQWL
DIVNKDLEII GKIATEPEKF EEQLEAQKAL KEEIDSKRPD FEFLVKIFNP FADIVAEDDA
IELENTLHNL SERYDDIGIR CMNCGKSLEE MKENINSFLA DTKDLSSWLD HIEKELEKFD
EMPVSTDELI VQSEKLSELV GAITERENLV SRVVEDSREL CMHTSGPEAM QLQYRIDALH
QRYSKIALIT DKKIDTMSTA IPLSEDYCIM YDELAGCLEK IERELEQSEY DTIPNQQQLL
QELSKELFDH RNQLEILNTK VVQLQGLSSE VKAEELRKQT RELQEHFMEL NDIVNRKNER
LSIVSSRNRE VFDEMDNLLD WFTQAHQHIL DSKPPTVDID NLKAQLKDQK IFNDDIISQK
TFLREIVGEV SKFVKGIDDP VSINSNEDLN NKINKVKYLA DETSKLSEAR LENLEEAYEL
CLVMEENFND LNDWLDNMED ELAATDVNIL SLKPEQLIKL KQQNSNLFAA IQTQKPMFEK
FDKNVNAFVT MTSPEDAANL QLFADEVFKR YEDIANIVLK REQELNNNLE DSTLIEDRLN
LMIDNFENIS ERIKNFDGIK AKPEGIKKQI SENETIIKLI KSKEIPYLRL QEDATELIKK
SSTTDILNNE IIKKVDYLNL LWNDIILFGD KRDSTLNNAL NASKDFWDSY SSCQDSIKNL
NNSITEIHLD MSSDPSEIEN NRIKLSTIID EYMSFAPLIE NLKFIGLNLS SYLESDERGL
VEHAISYVEA ENSAIGGLLN NLTNDFGQAI DKSTNYHTLF KKVMEFITNM EDVVYNLPPI
TAATIEDIQN ELANISNLRG QIDENLLLKE QLNSSAQDLF LTAQPSQIVA IKSPLNELNN
RWNKIFSTIS DRFHKLEKSL LETGQFSQAY DQIMFWIVKT AGSVDQITVT DGDLRSIEIN
LSKINVIKND VMAHEQSVID IKRAGKSLIS IDPSSENSIK GKLEELNNRW IDLNDTIDAL
ISSLESAKND ASTLDQELDG WLMWLDDIES DLGLNKPIGG LPETARTQLD DFLVLNAQVE
QRKDELNKLL EGKTNDNSNN SWSQQQHGKI QKKWDSLRKK MSDKHEKLKN ALEDAEKFQK
EIDEVAEFIG VGENYLSMLP PISSIPETIQ EQLQSHGEFN SKFQTNKKKL GELSTKGSKL
QFICEKKDSI PIKNKLTTMR HQFDKLNNKS LERMKSLENT LTNSTNYVEE HKDIINWIKD
NSVRMKEDPI ISTTGDRIRD QIDNENAFKN VLLEKTPLIN NLLKKGKSLE DFAPKNEKGI
ISKMNNSLTR DWDALNDASN HRIQLLHDAL LQNGKFEEAL ADVSNWLHEQ LPHLEEDLEM
KKLYGDVDNV NYLIKKHNKL KEDINDHSSA VIKVQKRYHD IMNKEPDAIT DDVKNEIDNM
VQNWEKINSL VEEKSIILED ALIKANDLDD KINDLLKWIG KTDNNLKKNS TLKPSQPEED
FLREQIDSLE YTLEEIDSKE PDFEDLLNVG EEILQKVHPS AEVPVKDSIN MITRRWNALK
NIIKEKRDVM KDSLKSFKDN EKLLDELTVF VENKQHELDD VLDISNVNQL EELAERFNQH
DKFKEQLSEK QEPIEMAIKG YKKALIAANI LHQNEPIDQI NNSKTDKKVK LGLLPTTHSP
RYFKGDKLNN SWKNLWMNSM TYEQALQERK DYLEELKRLE NFDFDEWKER YNEWNDHGKG
RVTDLFRRID KNGTGKVPRN IFIEAILASK FTTTPLEMEK VADVFDKGDG FIDAREFIKL
LRIDPRKSKP KTDEERIDEE ITRQAKRCTC AQRFPITHLG ASKGAVSYGF GQNTTMKRMV
RILQSTVMVR VGGGWEEIDS FLVKHDPCRA KGRTNVDLFY SGVQPGTNSD QIREFTHKSP
KTSTVTPARK NSGIENFKSP KQVLGYPTQG PITKIREKTE KSIPMFATPK RPSISLERKA
HVNLLQHCTS DSRIPRPTTS LNSSSRSTSR SDLNFLTDSR PPSRCSDISD FSDRPPSRIP
SLRKNKKMTS QHGSNV
//
