UniProt: A0A090LLN8

Database: UniProt
Entry: A0A090LLN8_STRRB

LinkDB:  A0A090LLN8_STRRB 
Original site:  A0A090LLN8_STRRB

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Ontology (4)   
   GO (4)   
Gene (1)   
   WORMBASE (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (13)   
   InterPro (8)   
   Pfam (3)   
   PROSITE (1)   
   SMART (1)   
All databases (19)   

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ID   A0A090LLN8_STRRB        Unreviewed;       476 AA.
AC   A0A090LLN8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Transcription factor collier {ECO:0000313|EMBL:CEF70705.1, ECO:0000313|WBParaSite:SRAE_X000003600.1};
GN   ORFNames=SRAE_X000003600 {ECO:0000313|EMBL:CEF70705.1,
GN   ECO:0000313|WBParaSite:SRAE_X000003600.1,
GN   ECO:0000313|WormBase:SRAE_X000003600};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF70705.1};
RN   [1] {ECO:0000313|EMBL:CEF70705.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_X000003600.1}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF70705.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_X000003600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU004489}.
CC   -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC       ECO:0000256|RuleBase:RU004489}.
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DR   EMBL; LN609530; CEF70705.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090LLN8; -.
DR   STRING; 34506.A0A090LLN8; -.
DR   EnsemblMetazoa; SRAE_X000003600.1; SRAE_X000003600.1; WBGene00265590.
DR   WBParaSite; SRAE_X000003600.1; SRAE_X000003600.1; WBGene00265590.
DR   WormBase; SRAE_X000003600; SRP06439; WBGene00265590; -.
DR   eggNOG; KOG3836; Eukaryota.
DR   OMA; FGSTTVW; -.
DR   OrthoDB; 3641706at2759; -.
DR   Proteomes; UP000035682; Chromosome X.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd11606; COE_DBD; 1.
DR   Gene3D; 1.10.287.4280; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR   InterPro; IPR032200; COE_DBD.
DR   InterPro; IPR038173; COE_DBD_sf.
DR   InterPro; IPR032201; COE_HLH.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR003523; Transcription_factor_COE.
DR   InterPro; IPR018350; Transcription_factor_COE_CS.
DR   PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10747:SF38; TRANSCRIPTION FACTOR COLLIER; 1.
DR   Pfam; PF16422; COE1_DBD; 1.
DR   Pfam; PF16423; COE1_HLH; 1.
DR   Pfam; PF01833; TIG; 1.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   PROSITE; PS01345; COE; 1.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|RuleBase:RU004489};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW   Metal-binding {ECO:0000256|RuleBase:RU004489};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   Transcription {ECO:0000256|RuleBase:RU004489};
KW   Transcription regulation {ECO:0000256|RuleBase:RU004489};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT   DOMAIN          256..343
FT                   /note="IPT/TIG"
FT                   /evidence="ECO:0000259|SMART:SM00429"
SQ   SEQUENCE   476 AA;  52630 MW;  5C35E1C60C1BDB98 CRC64;
     MFGFQEPTSS LLRSVKEEVN ISGASSILGQ HWPTAMLDAT AVENAQLVRA HFEKHPPNNL
     RKSNFFHFVI ALYDRTGQPV EIERTQFAGF VEKDKEVDGE NSRNGIHYKV QLAYASGLRA
     EQDLYVRLID SVTKTAIVYE GQDKNPEMCR VLLTHEVMCS RCCEKKSCGN RNETPSDPVI
     IDRYFLKFFL KCNQNCLKNA GNPRDMRRFQ VVIGTTPRVD GPLLAISENM FVHNNSKHGR
     RVKRSGSIDE TILAVCPTIK AICPSEGWTQ GGNTVIIIGE NFFDGVQVSF GSTTVWSENV
     QVITQHAIRV TVPPKQLPGV VDVTLSFKSK VFSRGNPGRF VYVSLTEPSI EFGFQRLQKL
     LPKYPGDPER MPKELILKRA AELAEALYNR TPADQLSHYA SAYSAHFDTS AYNQAAAASA
     AAVSNSLPSA VYQGNYHGTG VPNVSAASNF LNGSSFATFH SVNPFAATLH TSTRLA
//

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