GenomeNet

Database: UniProt
Entry: A0A090MYS2_STRRB
LinkDB: A0A090MYS2_STRRB
Original site: A0A090MYS2_STRRB 
ID   A0A090MYS2_STRRB        Unreviewed;       802 AA.
AC   A0A090MYS2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 24.
DE   SubName: Full=Cyclic nucleotide-binding domain and Potassium channel, voltage-dependent, EAG/ELK/ERG family and RmlC-like jelly roll fold domain and Cyclic nucleotide-binding-like domain-containing protein {ECO:0000313|EMBL:CEF67679.1};
GN   ORFNames=SRAE_2000234000 {ECO:0000313|EMBL:CEF67679.1,
GN   ECO:0000313|WormBase:SRAE_2000234000};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Panagrolaimoidea; Strongyloididae; Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF67679.1, ECO:0000313|Proteomes:UP000035682};
RN   [1] {ECO:0000313|EMBL:CEF67679.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682}, and ED321
RC   Heterogonic {ECO:0000313|EMBL:CEF67679.1};
RA   Aslett A.Martin.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_2000234000}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|WBParaSite:SRAE_2000234000};
RA   Magalhaes I.L.F., Oliveira U., Santos F.R., Vidigal T.H.D.A.,
RA   Brescovit A.D., Santos A.J.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|WBParaSite:SRAE_2000234000}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JAN-2017) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LN609529; CEF67679.1; -; Genomic_DNA.
DR   EnsemblMetazoa; SRAE_2000234000; SRAE_2000234000; WBGene00262550.
DR   WBParaSite; SRAE_2000234000; SRAE_2000234000; WBGene00262550.
DR   WormBase; SRAE_2000234000; SRP08242; WBGene00262550; -.
DR   OMA; YLWANRK; -.
DR   Proteomes; UP000035682; Chromosome 2.
DR   GO; GO:0034703; C:cation channel complex; IEA:EnsemblMetazoa.
DR   GO; GO:0097543; C:ciliary inversin compartment; IEA:EnsemblMetazoa.
DR   GO; GO:0030425; C:dendrite; IEA:EnsemblMetazoa.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0097730; C:non-motile cilium; IEA:EnsemblMetazoa.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IEA:EnsemblMetazoa.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IEA:EnsemblMetazoa.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0009454; P:aerotaxis; IEA:EnsemblMetazoa.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:EnsemblMetazoa.
DR   GO; GO:0003031; P:detection of carbon dioxide; IEA:EnsemblMetazoa.
DR   GO; GO:0050907; P:detection of chemical stimulus involved in sensory perception; IEA:EnsemblMetazoa.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IEA:EnsemblMetazoa.
DR   GO; GO:0048609; P:multicellular organismal reproductive process; IEA:EnsemblMetazoa.
DR   GO; GO:0010754; P:negative regulation of cGMP-mediated signaling; IEA:EnsemblMetazoa.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:EnsemblMetazoa.
DR   GO; GO:0042048; P:olfactory behavior; IEA:EnsemblMetazoa.
DR   GO; GO:0007602; P:phototransduction; IEA:EnsemblMetazoa.
DR   GO; GO:0040010; P:positive regulation of growth rate; IEA:EnsemblMetazoa.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:EnsemblMetazoa.
DR   GO; GO:0030516; P:regulation of axon extension; IEA:EnsemblMetazoa.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:EnsemblMetazoa.
DR   GO; GO:0040040; P:thermosensory behavior; IEA:EnsemblMetazoa.
DR   GO; GO:0043052; P:thermotaxis; IEA:EnsemblMetazoa.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR032406; CLZ_dom.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF16526; CLZ; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035682};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115,
KW   ECO:0000313|EMBL:CEF67679.1};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00903208};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00904256};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00903350};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00903851}.
FT   TRANSMEM    253    278       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    284    307       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    390    411       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    470    492       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      574    693       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED      719    764       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   802 AA;  92133 MW;  4FEC43EF6432105F CRC64;
     MLRRNKNDGR DNSIYNAPSY DKKNDHELKE KSNDIHKNTG NNMVKQDSVD SNNYPPRRNK
     SLKKKKNRTL KSQVSIEPIA NNSSNNNYIS GTRPMTIDNK QKDKSTDNDK TNINKSNDGQ
     RISPIVKITV PGTVNDQDSE LTDLDEGGGV EVDDSIIIQK NESPPLVNNL NSSNSINENL
     KKEELSNNDK STDKHNGTIQ PDKILQNKNN DDKEVSEEVP GGEQKPPEPP KPSYYKKFKE
     FLKVFVADKT SDWYYYWTGI VSIAFMYNLI VIIARVVFVD LNSGFMWIVW LSSDLISDII
     YMIDIFVKSR TGFLEQGLLV KDTKKIWIAY KNSTSAKLDI LCIIPLDYIF TYIIFDKPIA
     RFNRLIKVER IKSFMETTET RSSMPNVFRV FTVVCYIIVI IHWNACFYFA ISELIGLGSD
     SWVYGPLNTQ SLPEGVEDTL IRRYIYSFYW STLILTTIGE VPGPVQNIEF VFVTFDLMGG
     VLIFATIVGN VGSMISNMSA DRTEFQNKMD SIKQYMELRK VSKALENRVI KWFDYLWANK
     QNLSDQQVLK LLPDKLQAEI AMHVHFETLR KVRIFQDCEA GLLAELVLKL QLQVFSPGDY
     ICRKGDIGRE MYIVKRGKLQ VVADDGVKVF ATLQEGSVFG ELSILNIAGS KNGNRRTANV
     RSVGYTDLFV LNKQDLWNAL KEYPEARKML IAKGREILKK DNLLDENAPE EQNTVEEIAE
     ELQNSVKVLQ TRLARLTAEY TNTENKLRNR IEYLEKRLRK YQVISDIRNE DYMDTESIRH
     SLLSQEKARQ DALDYKPKDK NV
//
DBGET integrated database retrieval system