ID A0A091DFG4_FUKDA Unreviewed; 1206 AA.
AC A0A091DFG4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Fibronectin type III domain-containing protein 3B {ECO:0000313|EMBL:KFO29802.1};
GN ORFNames=H920_08789 {ECO:0000313|EMBL:KFO29802.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO29802.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO29802.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO29802.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FNDC3 family.
CC {ECO:0000256|ARBA:ARBA00038207}.
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DR EMBL; KN122563; KFO29802.1; -; Genomic_DNA.
DR RefSeq; XP_010630709.1; XM_010632407.2.
DR AlphaFoldDB; A0A091DFG4; -.
DR STRING; 885580.ENSFDAP00000009906; -.
DR Ensembl; ENSFDAT00000022843; ENSFDAP00000009906; ENSFDAG00000017805.
DR GeneID; 104867865; -.
DR CTD; 64778; -.
DR eggNOG; KOG0613; Eukaryota.
DR OMA; DTHFEIR; -.
DR OrthoDB; 316463at2759; -.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 9.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF11; FIBRONECTIN TYPE III DOMAIN-CONTAINING 3BA-RELATED; 1.
DR Pfam; PF00041; fn3; 8.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 9.
DR SUPFAM; SSF49265; Fibronectin type III; 6.
DR PROSITE; PS50853; FN3; 9.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1181..1204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 280..379
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 383..475
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 479..572
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 576..671
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 675..769
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 771..861
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 873..959
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 960..1054
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1058..1155
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 184..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1206 AA; 132923 MW; 38B0B51901F1D5D1 CRC64;
MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGEAAQQVIL VQVNPGETFT IRAEDGTLQC
IQGPAEVPMM SPNGSIPPIH VPPGYISQVI EDSTGVRRVV VTPQSPECYP PSYPSAMSPT
HHLPPYLAHP HFIHNSHTAY YPPVTGPGDM PPQFFPQHHL PPTIYGEQEI IPLYGMSSYI
TREDQYSKPP HKKLKDRQID RQNRLNSPPS SIYKSNCTTV YNGYGKGHSG GGGGGGGGGS
GGGPGIKKTE RRARSSPKSN DSDLQEYELE VKRVQDILSG IEKPQVSNIQ ARAVVLSWAP
PVGLSCGSHS GLSFPYSYEV ALSDKGRDGK YKIIYSGEEL ECNLKDLRPA TDYHVRVYAM
YNSVKGSCSE PVSFTTHSCA PECPFPPKLA HRSKSSLTLQ WKAPIDNGSK ITNYLLEWDE
GKRNSGFRQC FFGSQKHCKL TKLCPAMGYT FRLAARNDIG TSGYSQEVVC YTLGNIPQMP
SAPRLVRAGV TWVTLQWNKP EGCSPEEAVT YTLEIQEDEN DNLFHPKYTG EDLTCTVKNL
KRSTQYKFRL TASNMEGKSC PSEVLVCTTS PDRPGPPTRP LIKGPVTPHG FSVKWDTPKD
NGGSEILKYL LEITDGNSEA NQWEVAYSGS ATEYTFTHLK PGTLYKLRAC CISTGGHSQC
SESLPVRTLS IAPGQCRPPR VLGRPKHKEV HLEWDVPASE SGCEVSEYSV EMTEPEDVAS
EVYHGPELEC TVGNLLPGTV YRFRVRALND GGYGPYSDVS EITTATGPPG QCKAPCVSFT
PDGCILVSWE SPESLGADIS EYRLEWGEDE ESLELIYHGT DTCFEMRDLL PAAEYCCRLQ
AFNQAGAGPY SELVLCRTPA SAPDPVSTLC VLEEEPLNAY PDSPSVCLVL SWEEPCNNGS
EILSYNIDLG DSSITVGNTT THVVKDLLPE TTYWIRIQAV NEIGAGPFSQ FIKAKTRPLP
PLPPRLECAA AGPQSLKLKW GDSNSKTHAA DDMVYTLQLE DRNKRFISIY RGPSHTYKVQ
RLAEFTCYSF RIQAASEAGE GPFSETYTFS TTKSVPPTIK APRVTQLEGN SCEILWETVP
PMKGDPVNYI LQVLVGRESE YKQVYKGEEA TFQISGLQTN TDYRFRVCVC RRCLDTSQEL
SGAFSPSAAF VLQRSEVMLT GDMGSLDDPK MKSMMPTDEQ FAALIVLGFA TLSILFAFIL
QYFLMK
//
