GenomeNet

Database: UniProt
Entry: A0A091DH16_FUKDA
LinkDB: A0A091DH16_FUKDA
Original site: A0A091DH16_FUKDA 
ID   A0A091DH16_FUKDA        Unreviewed;       899 AA.
AC   A0A091DH16;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   SubName: Full=T-complex protein 1 subunit alpha {ECO:0000313|EMBL:KFO30372.1};
GN   ORFNames=H920_08197 {ECO:0000313|EMBL:KFO30372.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Bathyergidae; Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO30372.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO30372.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO30372.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular chaperone; assists the folding of proteins
CC       upon ATP hydrolysis. {ECO:0000256|SAAS:SAAS00901419}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00901396}.
CC   -!- SIMILARITY: Belongs to the TCP-1 chaperonin family.
CC       {ECO:0000256|RuleBase:RU004187}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KN122446; KFO30372.1; -; Genomic_DNA.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd03335; TCP1_alpha; 1.
DR   Gene3D; 1.10.560.10; -; 2.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   InterPro; IPR012715; Chap_CCT_alpha.
DR   InterPro; IPR017998; Chaperone_TCP-1.
DR   InterPro; IPR002194; Chaperonin_TCP-1_CS.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom.
DR   InterPro; IPR027413; GROEL-like_equatorial.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR027410; TCP-1-like_intermed.
DR   PANTHER; PTHR11353; PTHR11353; 2.
DR   Pfam; PF00118; Cpn60_TCP1; 2.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00304; TCOMPLEXTCP1.
DR   SUPFAM; SSF48592; SSF48592; 2.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 2.
DR   PROSITE; PS00751; TCP1_2; 1.
DR   PROSITE; PS00995; TCP1_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU004187};
KW   Chaperone {ECO:0000256|RuleBase:RU004187};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028990};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00901395};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU004187};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     44     62       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     82    103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    109    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    155    185       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    191    212       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    255       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       42    266       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      330    353       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   899 AA;  100353 MW;  D7A8926AA5E9EAA7 CRC64;
     MHHHFIQPQE QVLINRQDII NRKDAWDKQE FVRMSIQYML QHPAFHILLA LLLVTNAITI
     ALRTNSFLDQ KHYEFFSVID DIVLTTLICE VLLRWLSGFW IFWKDGWNVL NFFIVCMLVL
     GVLDVVNVSI TYCLRVLRLV HVCMAVEPLA RIIRVILQAG PGMAQIGVLI LFVMLVFALL
     GVTLFGESVP IHFGNLGVAL YTLFVCLTQD GWVDIYGDFR MKERDYALEI GGAIYFAIFI
     IIGGIIGMNL LVTVVTRNLE QITKTEELEQ QHQKNFSETG AEKEDWSHEL PLPHCTLACM
     EKPDLHQETL VGSPMSNLSE NMLHNFCLVL EEIEENLTQY KKIREELDNI VQEVRSIPFN
     QEQIEELMRR PFSMSLMESG SSMDLQNIAK QQDLFSALVS RAKMEGPLSV FGDRTTGEAI
     RSQNVMAAAS IANIVKSSLG PVRLDKMLVD DTGDVTISND GATILKLLEV EHPAAKVLCE
     LADLQDKEVG DGTTSVSVII LNCWYRNGDF FSNMVVDAVL AVKYTDSRGQ PRYPVNSVNV
     LKAHGRSQTE SMLINGYALN CVVGSQGMPK RIVNAKIACL DFSLQKTKMK LGVQVLIIDP
     EKLDQIRQRE SDITKERIQK ILATGANVIL TTGGIDDMCL KYFVESGGMA VRRVLKRDLK
     RIAKASGATV LSTLANLEGE ETFEATVLGQ AEEVVQKRIC DDELILIRNT KARTSASIIL
     CGANDFMCDE MERSLHDALC VVKRVLESKS VVPGGGAVEA ALSIYLENYT TSMGSREQLA
     IAEFARSLLV IPNTLAVNAA EDSTDLVAKL RAFHNEAQVN PERKNLKWIG LDLINGKPRD
     KKQAGVFEPT IVKVKSLKFA TEAVITILRI DDLIKLHPES KDDKHGGYED AVHSGALDD
//
DBGET integrated database retrieval system