ID   A0A091DNA7_FUKDA        Unreviewed;       628 AA.
AC   A0A091DNA7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=DNA repair protein XRCC1 {ECO:0000313|EMBL:KFO33619.1};
GN   ORFNames=H920_04965 {ECO:0000313|EMBL:KFO33619.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO33619.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO33619.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO33619.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KN122065; KFO33619.1; -; Genomic_DNA.
DR   RefSeq; XP_010621573.1; XM_010623271.2.
DR   AlphaFoldDB; A0A091DNA7; -.
DR   STRING; 885580.ENSFDAP00000003074; -.
DR   Ensembl; ENSFDAT00000016794; ENSFDAP00000003074; ENSFDAG00000012606.
DR   GeneID; 104861706; -.
DR   CTD; 7515; -.
DR   eggNOG; KOG3226; Eukaryota.
DR   OMA; PEWIYAI; -.
DR   OrthoDB; 1334125at2759; -.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR   GO; GO:0000012; P:single strand break repair; IEA:InterPro.
DR   CDD; cd17725; BRCT_XRCC1_rpt1; 1.
DR   CDD; cd17707; BRCT_XRCC1_rpt2; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 2.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR045080; BRCT_XRCC1_rpt1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR002706; Xrcc1_N.
DR   PANTHER; PTHR11370:SF6; DNA REPAIR PROTEIN XRCC1; 1.
DR   PANTHER; PTHR11370; DNA-REPAIR PROTEIN XRCC1; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF01834; XRCC1_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF52113; BRCT domain; 2.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS50172; BRCT; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT   DOMAIN          310..398
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          533..624
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          221..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..278
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..466
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..481
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        482..503
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  68869 MW;  53C8F5846A4E9827 CRC64;
     MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KCISVVLQLE KEEQIHSMDI
     GNNGSAFVEV LVGSSAGGAS EQDYEVLLVM SSFMSPSESR SGSNPSRVRM FGPDKLVRTA
     AEKRWDRIKI VCSQPYSKDS PYGLSFIRLR SPPDKEEAEV PSQKVTMTKL GQFRVKEEDE
     SASSLRPGAL FFGRINKTSP ATASDPAGPS YAAATLQASA SPLSKAVGST TKPQESTKGK
     RKLDLNVEER KTPSKPSAQL SPPPLKRPKL PAPTRSPAAA PAPATAQRAV PGKPRGEGTE
     PRGARAGPQE LGRILEGVVV VLSGFQNPFR SDLRDKALEL GAKYRPDWTP DSTHLICAFA
     NTPKYSQVLG LGGRIVRKEW VLDCHRMRRR LPSRRYLMAG PNSSSEDEAG SPSGSGGEEA
     PRLPRKRPQT KAKPPLAAGS SSPQKPPSPK ETKAASGGPQ ENSDTEEEQS AGWDNGAEES
     GDTEDELRRV AEHKEHRPPA GQEENGEDPY AGSTDENTDS EGQPEPPDQP IPELPDFFQG
     KHFFLYGEFP GDERRKLIRY VTAFNGELED YMSDRVQFVI TAQEWDPSFE EALMDNPSLA
     FVRPRWIYSC NEKQKLLPHQ LYGVVPQA
//