ID A0A091DSH3_FUKDA Unreviewed; 2469 AA.
AC A0A091DSH3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Putative E3 ubiquitin-protein ligase MYCBP2 {ECO:0000313|EMBL:KFO34057.1};
GN ORFNames=H920_04541 {ECO:0000313|EMBL:KFO34057.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO34057.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO34057.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO34057.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN122017; KFO34057.1; -; Genomic_DNA.
DR STRING; 885580.ENSFDAP00000005583; -.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.120.820; PHR domain; 2.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR012983; PHR.
DR InterPro; IPR038648; PHR_sf.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR45943; E3 UBIQUITIN-PROTEIN LIGASE MYCBP2; 1.
DR PANTHER; PTHR45943:SF1; E3 UBIQUITIN-PROTEIN LIGASE MYCBP2; 1.
DR Pfam; PF08005; PHR; 2.
DR Pfam; PF00415; RCC1; 1.
DR Pfam; PF13540; RCC1_2; 1.
DR PRINTS; PR00633; RCCNDNSATION.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS00626; RCC1_2; 2.
DR PROSITE; PS50012; RCC1_3; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT REPEAT 572..627
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 1000..1050
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 1051..1108
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 1276..1397
FT /note="PHR"
FT /evidence="ECO:0000259|Pfam:PF08005"
FT DOMAIN 1519..1676
FT /note="PHR"
FT /evidence="ECO:0000259|Pfam:PF08005"
FT REPEAT 2134..2227
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REGION 224..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 580..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 939..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1384..1416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2105..2135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..965
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2107..2135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2469 AA; 268889 MW; 1397466FC262A171 CRC64;
MLSAAGSFPL RATRAEAVVV AAALVALLLS GRALADRYRR IYTAALSDRD QGGGSAGHPA
SRCVSTVPFH ASHAACAPVC VHPCVESACV STYVRSQLSS SQLLMLVVEA LRQVRGRNKK
TLNKKKLKRK QKSKSKVKTR SKVPFGDFLQ VACDIQEEME SQGLLYSFSS ALTSFVFLSE
NLENTVIIPD IKLHSNPSAF NIYCNVRHCV LEWQKKEISL AAASKNSVQS GESDSDEEEE
SKEPPIKLPK IIEVGLCEVF ELIKETRFSH PSLCLRSLQA LLNVLQGQQP EGLQSEPPEV
LESLFQLLLE ITVRSTGMND STGQSLTALS CACLFSLVAS WGETGRTLQA ISAILTNNGS
HACQTIQVPT ILNSLQRSVQ AVLVGKIQIQ DWFSNGIKKA ALMHKWPLKE VSVDEDDQCL
LQNDGYFLYL LCKDGLYKIG SGYSGTVRDG FVVRIFATST EPVLQQELQL KLARKCLHAC
GISLFDLEKD LHIISTGFDE ESAILGAGRE FALMKTANGK IYYTGKYQSL GIKQGGPSAG
KWVELPITKS PKIVHFSVGH DGSHALLVAE DGSIFFTGSA SKGEDGESTK SRRQSKPYKP
KKIIKMEGKI VVYTACNNGS SSVISKDGEL YMFGKDAIYS DSSSLVTDLK GHFVTQVAMG
KAHTCVLMKN GEVWTFGVNN KGQCGRDTGA MNQGGKGFGV ENMATAMDED LEEELDEKDE
KSMMCPPGMH KWKLEQCMVC TVCGDCTGYG ASCVSSGRPD RVPGGICGCG SGESGCAVCG
CCKACARELD GQEARQRGIL DAVKEMIPLD LLLELQVLYI TPVVVIVILI NNLAVPVPGV
NIEEHLQLRQ EEKRQRVIRR QRLEEGRAMA KIGSFEEDLA QQVWSGGGSR KAIRLCPAGD
GHLIDHLPPG FLAQDMLGPL VFAGPIFMNN REQALARLRS HPAQLKHKRD KHKDGNGERG
EKDASKITTY PPGSVRFDCE LRAVQVSCGF HHSVVLMENG DVYTFGYGQH GQLGHGDVNS
RGCPTLVQAL PGPSTQVTAG SNHTAVLLLD GQVFTFGSFS KGQLGRPILD VPYWNAKPAP
MPNIGSKYGR KATWIGASGD QTFLRIDEAL INSHVLATSE IFASKHIIGL VPASISEPPP
FKCLLINKVD GSCKTFNDSE QEDLQGFGVC LDPVYDVIWR FRPNTRELWC YNAVVADARL
PSATDMQSRC SILSPELALP TGSRALTTRS HAALHILGCL DTLAAMQDLK MGIASTEEET
QAVLKVYSKE DYSVVNRFES HGGGWGYSAH SVEAIRFCAD TDILLGGLGL FGGRGEYTAK
IKLFELGPDG GDHETDGDLL AETDVLAYDC AAREKYAMMF DEPVLLQAGW WYVAWARVSG
PSSDCGSHGQ ASITTDDGLP TSDSSASKGK QQTSEPVHIL KRSFARTVSV DIQEANFKTS
SSRLLAAVMS ALCHTSVKLT SIFPIAYDGE VLLRSIVKQV STENDSTLVH RFPLLVTHME
KLSQVDGLNS LHAVKASANR FTKTSQGRSW NTGNGSPDAI CFSVDKPGIV VVGFSVYGGG
GIHEYELEVL VDDSEHVGDS THSHRWTSLE LVKGTYTTDD SPSDIAEIRL DKVVPLKENV
KYAVRLRNYG SRTANGDGGM TTVQCPDGVT FTFSTCSLSS NGTNQTRGQI PQILYYRSEF
DGDLQSQLLS KANEEDKNCS RALSVVSTVV RAAKDLLHRA LAVDADDIPE LLSSSSLFSM
LLPLIIAYIG PVAAAIPKVA VEVFGLVQQL LPSVAILNQK YAPPAFNPNQ STDSTTGNQP
EQGLSACTTS NHYAVIESEH PYKPACVMHY KVTFPECVRW MTIEFDPQCG TAQSEDVLRL
LIPVRTIQIS GYGPKLTSVH ENLNSWIELK KFSGPSGWPT MVLVLPGNEA LFSLETASDY
VKDDKASFYG FKCFAIGYEF SPGPDEGVIQ LEKELANLGG VCAAALMKKE LALPVGNELE
EDLEILEEAA LQVCKTHSGI LGKGLALSHS PTILEALEGN LPLQIQSNEQ SFLDDFIACV
PGSSGGRLAR WLQPDSYADP QKTSLILNKD DIRCGWPTTI TVQTKDQYGD VVHVPNMKVE
VKAVPVSQKK SSLQQEQAKK PQRIPGSPAV TSASSNTDLT FGGLASPKLD VSYEPMIVKE
ARYIAITMMK VYENYSFEEL RFASPTPKRP SENMLIRVNN DGTYCANWTP GAIGLYTIHV
TIDGIEIDAG LEVKVKDPPK GMIPPGTQLV KPKAEPQPNK VRKFVAKDSA GLRIRSHPSL
QSEQIGIVKV NGTITFIDEI HNDDGVWLRL NDETIKKYVP NMNGYTEAWC LSFNQHLGKS
LLVPVDEAKT NTDDFFKDIN SCCPQEATMQ EQDMPFFRGG PGMYKVVKTG PSGHNIRSCP
NLRGIPIGML VLGNKVKAVG EVTNSEGTWV QLDKNSMVEF CESDEGEAWS LARDRGGNQY
LRHEDGKLA
//
