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Database: UniProt
Entry: A0A091EH55_FUKDA
LinkDB: A0A091EH55_FUKDA
Original site: A0A091EH55_FUKDA 
ID   A0A091EH55_FUKDA        Unreviewed;      2257 AA.
AC   A0A091EH55;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   10-MAY-2017, entry version 15.
DE   SubName: Full=Voltage-dependent T-type calcium channel subunit alpha-1H {ECO:0000313|EMBL:KFO34751.1};
GN   ORFNames=H920_03779 {ECO:0000313|EMBL:KFO34751.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Bathyergidae; Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO34751.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO34751.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO34751.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN121905; KFO34751.1; -; Genomic_DNA.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IEA:InterPro.
DR   GO; GO:0070509; P:calcium ion import; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005445; VDCC_T_a1.
DR   InterPro; IPR030160; VDCC_T_a1H.
DR   PANTHER; PTHR10037:SF227; PTHR10037:SF227; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR01629; TVDCCALPHA1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000028990};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22   2257       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001872777.
FT   TRANSMEM     45     64       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    159       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    269    290       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    296    321       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    693    711       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    723    744       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    814    836       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    891    914       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1236   1257       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1269   1298       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1333   1355       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1434   1458       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1520   1537       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1557   1576       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1655   1675       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1687   1707       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1741   1762       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        3    332       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      692    919       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1196   1468       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1520   1772       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   2257 AA;  249620 MW;  798F7E9DE00E5A25 CRC64;
     MCTWFEHVSM LVIMLNCVTL GMFRPCEDVA CRSERCSILE AFDDFIFAFF AVEMVIKMVA
     LGLFGQKCYL GDTWNRLDFF IVMAGMMEYS LDGHNVSLSA IRTVRVLRPL RAINRVPSMR
     ILVTLLLDTL PMLGNVLLLC FFVFFIFGIV GVQLWAGLLR NRCFLDSTFV RNNNLTFLRP
     YYQPEEGEEN PFICSSRRDN GMQKCSHIPS RRELRVQCTL GWEAYGQPPA EAAGAGRNGC
     INWNQYYNVC RSGDSNPHNG AISFDNIGYA WIAIFQVITL EGWVDIMYYV MDAHSFYNFI
     YFILLIIVGS FFMINLCLVV IATQFSETKQ RENQLMREQR ARYLSNDSTL ASFSEPGSCY
     EELLKYMGHV FRKVKRRSLR LYARWQSRWH KKADPSATLH GQGPGQRQRQ AGRHAASVHH
     LVYHHHHHHH HHYHFSHGGP RRPDPDPSDT RLVRAGVPPC PPSPSQGPPN SESVHSIYHA
     DCHVEGPQER ARLAHAAATA TASLKLASGL GTMNYPTILP SSIDASKGST SPKPKGKRNA
     GALGATGHSP LSLGSPNPCE KIQHAVGEHG LGRDPSHLSG LNVPCSLPSP PAGTLTCALK
     SCPYCASALE DPELEFSGSE SGDSDAHGVY EFTQDVRHGD CRDAMQTPPT VDVPSQGSVR
     RPQGPAASGE PGGLGRLWAS FGSKLRRIVD SKYFNRGIMV AILINTLSMG VEYHEQPDEL
     TNALEISNIV FTSMFALEML LKLLACGPLG YIRNPYNIFD GIIVVISVWE IVGQADGGLS
     VLRTFRLLRV LKLVRFLPAL RRQLVVLMKT MDNVATFCML LMLFIFIFSI LGMHLFGCKF
     SLKTDTGDTV PDRKNFDSLL WAIVTVFQIL TQEDWNVVLY NGMASTSSWA ALYFVALMTF
     GNYVLFNLLV AILVEGFQAE GDANRSDTDE DKTSTRFEED FDKLRDLQAT EMKMYSLAVT
     PNGHLEGRGS LPPPLIMHTA ATPMPTPRSS PHLDAAHSLL DSRRSSSGSV DPQLVDQKSL
     ASLRSSPCTH WGPNSAWSSR RSSWNSLGRA PSLKRRSQCG ERESLLSGEG KGSTDDEAED
     GRPGVVTCPL RRAESLDHRN ALDLRPPRLA TLLPTKLHDC PGQTVALPSE FFLRIDSHRE
     EAADLEDDVE DSCCFRLHKV LEPYTPQWCR SRESWALYLF SPQNRLRTFC QKVIAHKMFD
     HVVLLFIFLN CITIALERPD IDPSSTERAF LSVSNYIFTA IFVSEMMVKV VALGLLWGEH
     AYLQSSWNVL DGLLVLVSLV DIVVAMASAG GAKILGILRV LRLLRTLRPL RVISRAPGLK
     LVVETLISSL RPIGNIVLIC CAFFIIFGIL GVQLFKGKFY FCDGADTRNI STKAECRAAH
     YRWVRRKYNF DNLGQALMSL FVLSSKDGWV NIMYDGLDAV GIDQQPVQNH NPWMLLYFIS
     FLLIVSFFVL NMFVGVVVEN FHKCRQHQEA EEARRREEKR LRRLERKRRS TFPSPEAQRR
     PYYADYSHTR RSVHTLCTSH YLDLFITFII GLNVITMSME HYNQPKSLDE ALKYCNYVFT
     IVFVFEAALK LVAFGFRRFF KDRWNQLDLA IVLLSIMGIA LEEIEINAAL PINPTIIRIM
     RVLRIARVLK LLKMATGMRA LLDTVVQALP QVGNLGLLFM LLFFIYAALG VELFGRLECS
     EDNPCEGLSR HATFANFGMA FLTLFRVSTG DNWNGIMKDT LRECTREDKH CLSYLPALSP
     IYFVTFVLVA QFVLVNVVVA VLMKHLEESN KEAREDAEMD AEVELELAQG PPAQPLPGAQ
     DSPGCGPDAP NLVVRKVSVS RMLSLPSDSY MFRPVVPAAA PQPVQEVEME TYSAAPSGQA
     TSAHSPPSEP CASLQVPPAT SSPARGSDPQ CAALPRGTPR SPSLGRLLCR QEAVHTESLE
     GQLDGPGDSG PDSTGPVEKT PVRKASLGAS LQSPPHSPRP ASVRTRKHTF GQHCISSRLL
     APGGDEAEAA DPADEEVRHI TSSAHSWPAA EPHSPETSPA ASPAARGIAG SRRDLHRLCS
     VDTQGFPDAP SRADTQRWPS VELGGADGHL EPGEVKARVP ELEPALGARR KKKMSPPCIS
     VDPPAEDEGS ARPSVAEGSS TLRRRTPSCE AAPHRDFPEP SEGTGGDPAA KGDRWGQVPC
     RAEHLTVPSF AFEPLNMGGP SGSPFLDSSQ SVTPEPRVSS SGAAVPLDPH ETEPSMPSGD
     PSERGRGLYL MVPGTPVKKL GSSSATPAPG DSADEPV
//
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