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Database: UniProt
Entry: A0A091EKX7_CORBR
LinkDB: A0A091EKX7_CORBR
Original site: A0A091EKX7_CORBR 
ID   A0A091EKX7_CORBR        Unreviewed;       494 AA.
AC   A0A091EKX7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 21.
DE   SubName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 {ECO:0000313|EMBL:KFO57287.1};
DE   Flags: Fragment;
GN   ORFNames=N302_03867 {ECO:0000313|EMBL:KFO57287.1};
OS   Corvus brachyrhynchos (American crow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC   Corvus.
OX   NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO57287.1, ECO:0000313|Proteomes:UP000052976};
RN   [1] {ECO:0000313|EMBL:KFO57287.1, ECO:0000313|Proteomes:UP000052976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO57287.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK718521; KFO57287.1; -; Genomic_DNA.
DR   Proteomes; UP000052976; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR030173; HCN4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF375; PTHR10217:SF375; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000052976};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00920158, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM     12     29       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     35     54       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    234    259       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      337    452       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFO57287.1}.
FT   NON_TER     494    494       {ECO:0000313|EMBL:KFO57287.1}.
SQ   SEQUENCE   494 AA;  57781 MW;  BC3FA09A55B045A2 CRC64;
     SLSRFYWDLT MLLLMVGNLI IIPVGITFFK DENTTPWIVF NVVSDTFFLI DLVLNFRTGI
     VVEDNTEIIL DPQRIKMKYL KSWFVVDFIS SIPVDYIFLI VETRIDSEVY KTARALRIVR
     FTKILSLLRL LRLSRLIRYI HQWEEIFHMT YDLASAVVRI VNLIGMMLLL CHWDGCLQFL
     VPMLQDFPDD CWVSLNRMVN DSWGKQYSYA LFKAMSHMLC IGYGQQAPVG MSDVWLTMLS
     MIVGATCYAM FIGHATALIQ SLDSSRRQYQ EKYKQVEQYM SFHKLPADMR QRIHDYYEHR
     YQGKMFDEES ILGELSEPLR EEIINFNCRK LVASMPLFAN ADPNFVTSML TKLKFEVFQP
     GDYIIREGTI GKKMYFIQHG VVSVLTKGNK ETKLADGSYF GEICLLTRGR RTASVRADTY
     CRLYSLSVDN FNEVLEEYPM MRRAFETVAL DRLDRIGKKN SILLHKVQHD LNSGVFNYQE
     NEIIQQIVQH DREM
//
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