ID   A0A091F251_CORBR        Unreviewed;       292 AA.
AC   A0A091F251;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Histamine N-methyltransferase {ECO:0000313|EMBL:KFO62609.1};
GN   ORFNames=N302_02282 {ECO:0000313|EMBL:KFO62609.1};
OS   Corvus brachyrhynchos (American crow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC   Corvus.
OX   NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO62609.1, ECO:0000313|Proteomes:UP000052976};
RN   [1] {ECO:0000313|EMBL:KFO62609.1, ECO:0000313|Proteomes:UP000052976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO62609.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK719330; KFO62609.1; -; Genomic_DNA.
DR   RefSeq; XP_008636430.1; XM_008638208.2.
DR   AlphaFoldDB; A0A091F251; -.
DR   STRING; 85066.A0A091F251; -.
DR   GeneID; 103619651; -.
DR   KEGG; cbrc:103619651; -.
DR   OrthoDB; 5388438at2759; -.
DR   Proteomes; UP000052976; Unassembled WGS sequence.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR016673; HHMT-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13489; Methyltransf_23; 1.
DR   PIRSF; PIRSF016616; HHMT; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51597; SAM_HNMT; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:KFO62609.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW   Transferase {ECO:0000313|EMBL:KFO62609.1}.
FT   BINDING         28
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016616-2"
FT   BINDING         283
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016616-2"
SQ   SEQUENCE   292 AA;  33418 MW;  353E93272EAC988A CRC64;
     MASPMRSLLA DPDRYLQSFR LFLERSTEHQ CMQEFVERQL PGVIASIGNG KSTINVLSIG
     GGAGEMDLQI LSKIRARYPE ATINNEVIEP SADQISKYKE RVAQASNLEN IKFTWHKETA
     YEYESRVNAE KKTKKWDFIH MIQMLYYVRD IPATIRYFHS LLESQAKLLI ILVSDFCGWE
     TLWKKYGSSF PLEDLCSYVS SADLPRMLDS AGLKYQLYEL PSRMDITSCF IEGDKDGELL
     LDFLTETLDF AKTAPPELKH QLMEDLRKPG CSENKDGKVF FNNNLGVIVI DP
//