ID   A0A091F565_CORBR        Unreviewed;       526 AA.
AC   A0A091F565;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Cochlin {ECO:0000256|ARBA:ARBA00013828};
DE   Flags: Fragment;
GN   ORFNames=N302_01732 {ECO:0000313|EMBL:KFO63694.1};
OS   Corvus brachyrhynchos (American crow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC   Corvus.
OX   NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO63694.1, ECO:0000313|Proteomes:UP000052976};
RN   [1] {ECO:0000313|EMBL:KFO63694.1, ECO:0000313|Proteomes:UP000052976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO63694.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the control of cell shape and motility in the
CC       trabecular meshwork. {ECO:0000256|ARBA:ARBA00003388}.
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DR   EMBL; KK719449; KFO63694.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091F565; -.
DR   STRING; 85066.A0A091F565; -.
DR   Proteomes; UP000052976; Unassembled WGS sequence.
DR   CDD; cd01472; vWA_collagen; 1.
DR   Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR004043; LCCL.
DR   InterPro; IPR036609; LCCL_sf.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR24020:SF36; COCHLIN; 1.
DR   PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR   Pfam; PF03815; LCCL; 1.
DR   Pfam; PF00092; VWA; 2.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00603; LCCL; 1.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF69848; LCCL domain; 1.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS50820; LCCL; 1.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000052976}.
FT   DOMAIN          3..96
FT                   /note="LCCL"
FT                   /evidence="ECO:0000259|PROSITE:PS50820"
FT   DOMAIN          141..326
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          343..513
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          111..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO63694.1"
FT   NON_TER         526
FT                   /evidence="ECO:0000313|EMBL:KFO63694.1"
SQ   SEQUENCE   526 AA;  57069 MW;  B5D749D6775A18C8 CRC64;
     SLASTAITCF TRGLDLRKGT EDVLCPANCP LWQFYVFGDG VYASLSSVCG AAIHRGVITN
     AGGAVRVQTL PGQENYPAVN ANGIQSQVLS RWASSFSVTA GTKNTALESV GRSVSTARPS
     TGKRPKKTLD KKAGNKDCKA DIAFLIDGSY NIGQRRFNLQ KNFVGKVAVM LGIGTEGPHV
     GVVQASEHPK IEFYLKNFTA AKEVLFAIKE LGFRGGNSNT GKALKHTAQK FFSVENGARK
     GIPKIIVVFL DGWPSDDLEE AGIVAREFGV NVFIVSVAKP TTEELGMVQD IGFVDKAVCR
     NNGFFSYQMP TWFGTTKYVK PLVQKLCSHE QMLCSKTCYN SVNIGFLIDG SSSVGESNFR
     LILEFVSNVA KAFEISDIGS KVAAVQFTYD QRTEFSFTDH VTKEKVLSAI RNIRYMSGGT
     ATGDAISFTT RNVFGPVKDG PNKNFLIVLT DGQSYDDVRG PAAAAQKAGI TVFSVGVAWA
     PLDDLKDMAS EPRESHTFFT REFTGLEQMV PDIIRGICKD FLDSKQ
//