ID A0A091FM95_CORBR Unreviewed; 524 AA.
AC A0A091FM95;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 30.
DE SubName: Full=T-lymphoma invasion and metastasis-inducing protein 2 {ECO:0000313|EMBL:KFO62450.1};
DE Flags: Fragment;
GN ORFNames=N302_02931 {ECO:0000313|EMBL:KFO62450.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO62450.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO62450.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO62450.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK719263; KFO62450.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091FM95; -.
DR STRING; 85066.A0A091FM95; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd01255; PH2_Tiam1_2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR043537; Tiam1/Tiam2/Sif.
DR PANTHER; PTHR46001:SF5; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM2; 1.
DR PANTHER; PTHR46001; TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052976}.
FT DOMAIN 1..114
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 321..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..440
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO62450.1"
FT NON_TER 524
FT /evidence="ECO:0000313|EMBL:KFO62450.1"
SQ SEQUENCE 524 AA; 59576 MW; 90DEE8DE52DD17BD CRC64;
FQKLLFSLGG SFLYYADHFK LYSGFCANHI KVQKVLERAK TDSAFKTFLD ARNPTKQHSS
TLESYLIKPV QRVLKYPLLL KELVSLTDNE SEEHYHLTEA LKAMEKVASH INEMQKIYED
YGTVFDQLVA DQSGTEKEVT ELSMGELLMH STVTWLNPFP SLGKARKDLE LTVFVFKRAV
ILVYKENYKL KKKMPTNVRA AHNYGDLDPF KFRWLIPLSA LQVRLGNTAG TENSCIWELI
HTKSELEGRP ETIFQLCSSD SENKTNIVKV IRSILRENFR RHIKCELPLE KTCKDRLIPL
KNRVPATAKL ASTRSLKVLK NSSSSEWNGD QGKSTFQDSD ECSLSSSTQS SSCHTSESIQ
EPKSSSPNKH TETTASDFSN VLVKESDILS DDDDDEDYRS LKKGSPTKDI EIQFQRLKIS
EEPGADSERD QAAENEEGDG FQRAEHPKLV RGHFCPVKRK VNSTKRNRGT LMAMQERHQS
LDSHSDAANL DLNSILEREF SVQSLTSVVN EDCFYEAVER HGKS
//
