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Database: UniProt
Entry: A0A091FZT5_9AVES
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ID   A0A091FZT5_9AVES        Unreviewed;       499 AA.
AC   A0A091FZT5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 21.
DE   SubName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 {ECO:0000313|EMBL:KFO74309.1};
DE   Flags: Fragment;
GN   ORFNames=N303_11516 {ECO:0000313|EMBL:KFO74309.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO74309.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO74309.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO74309.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL447511; KFO74309.1; -; Genomic_DNA.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR030173; HCN4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF375; PTHR10217:SF375; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053760};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00920158, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM      6     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    258       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      336    442       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFO74309.1}.
FT   NON_TER     499    499       {ECO:0000313|EMBL:KFO74309.1}.
SQ   SEQUENCE   499 AA;  58293 MW;  109280D5E3E86F45 CRC64;
     RFYWDLIMLL LMVGNLIILP VGITFFKDEN TPPWIVFNVL SDTFFLADLV LNFRTGIVVE
     DNTEIILDPH TIKMKYLKSW FLVDFISSIP VDYIFLIVDL ETQVDSDVYK TARALRIVRF
     TKILSLLRLL RLSRLIRYIH QWEEIFHMTY DLASAVVRIF NLIGMMLLLC HWDGCLQFLV
     PMLQDFPEDC WVSINHMVND SWGKQYSHAL FKAMSHMLCI GYGQQAPEGM TDVWLTMLSM
     IVGATCYAMF IGHATALIQS LDSSRRQYQE KYKQVEQYMS FHKLPGDTRQ RIHEYYEHRY
     QGKMFDEENI LGELSEPLKE EIINFNCRNL VANMPLFANA DPNFVTAMLT KLRFEVFQPG
     DFIIREGTVG KKMYFIQHGV VSILTKGNKE TKLSDGSYFG EICLLTRGRR TASVRADTYC
     RLYSLSVDNF NEVLEEYPMM RRAFETVAMD RLDRIGKKNS ILLRKRAEHS TGPMNNEIIQ
     QIVKHDQDMA HNIQDLQQM
//
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