ID A0A091GAK4_9AVES Unreviewed; 2199 AA.
AC A0A091GAK4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=ATP-binding cassette sub-family A member 1 {ECO:0000313|EMBL:KFO78993.1};
DE Flags: Fragment;
GN ORFNames=N303_06561 {ECO:0000313|EMBL:KFO78993.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO78993.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO78993.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO78993.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL447973; KFO78993.1; -; Genomic_DNA.
DR STRING; 55661.A0A091GAK4; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF34; PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KFO78993.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 615..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 752..772
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 793..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1318..1339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1626..1648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1668..1694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1706..1725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1737..1761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1824..1846
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 889..1120
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1883..2115
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO78993.1"
FT NON_TER 2199
FT /evidence="ECO:0000313|EMBL:KFO78993.1"
SQ SEQUENCE 2199 AA; 247151 MW; EC9B821A6E9B25E7 CRC64;
QFQLLIEVAW PLFIFFILIS VRLSYPPYEQ HECHFPNKAM PSAGTLPWIQ GIICNANNPC
FRYPTPGESP GIVGNFNASI VSRLFSDAKR LLLYSQQDTS IKDVQKVLGK LRKLGNISSS
DLKLRDVLID NETFSDFLHS NVSMPLSAVQ ELLDAKINLQ QVVVSGYRMR LRDLCNSSTL
SEFLVIQNQT VAMDSEAFIC NLPKEKLLAA ERAFRANLNP LKPLQSGKIS FANPVPMPAF
ALFSHLPVQL LSMKSWSDMR QEVMFLNNVN ASNSSTEIYQ AVSRIVCGHP EGGGLKIKSL
NWYEDNNYKA LFGGNSTEED VANFYDNSTT PYCNELMKNL ETSPLSRIIW RALKPLLIGK
ILYTPDTPAI RKVMTEVNRT FQELGVFRDL GGMWEEMSPK IWTFMESSQE MDLIRTLLKG
KALWDLHLPA SNWTVEDVAR FLSNHPEDFE GANGTVYTWV DAFNETDLAI QTISRFMECV
NLDKLEPVAT EVRLINKSLE LLDERRFWAG IVFTEIAPDS VELPQHVKYK IRMDIDNVER
TNKIKDAYWD PGPRADPFED MRYVWGGFAY LQDVVEQAII RVLTGTEKKT GVYVQQMPYP
CYVDDIFLRV MSRSMPLFMT LAWIYSVAVI IKGIVYEKEA RLKETMRIMG LDNGILWLSW
FISSLIPLLM SAGLLVLILK MGNLLPYSDP SVVFVFLSIF GVVTILQCFL ISTVFSRANL
AAACGGIVYF TLYLPYVLCV AWQDYISFSL KIFASLLSPV AFGFGCEYFA LFEEQGVGVQ
WDNFFESPLE EDGFSITTSA VMMLFDTFLY GVMTWYIESV FPGQYGIPRP WYFPFTKSYW
FGEEQQDRQH LHPDQKGSSE VSFKTCYISL LCFLLVCKEE EPVHLSLGVS IQNLVKVYRD
GKKVAVDGLT LNFYEGQITS FLGHNGAGKT TTMSILTGLF PPTSGTAFIL GKDIRSELST
IRQNLGVCPQ HNVLFDLLTV EEHIWFYARL KGLPEKKVKE EMDQMATDVG LPHKLKSRTS
KLSGGMQRKL SVALAFVGGS KVVILDEPTA GVDPYSRRGI WELLLKYRQG RTIILSTHHM
DEADILGDRI AIISHGKLCC VGSSLFLKNQ LGTGYYLTLV KKDVDSSLSS CRNSSSTVSY
LKKQYEHHLF FLVVLDVSAI SNLITKHVSE ARLVEDIGHE LTYVLPYKAA KEGAFVELFH
EIDDRLSDLG ISSYGISETT LEEVIQLITA LFSDGMLPAR RNRRVFGDRQ SCLRPFTEDD
VFDPNDSDID PESRETDLLS GVDGKGSYQM KGWKLTQQQF MALLWKRLLI AKRSRKGFFA
QIVLPAVFVC IALMFSLIVP PFGKYPSLEL QPWMYDEQYT FISNDAPEDA GTQRLLDALL
DKPGFGTRCM PGHSIPDTPC TMGQTEWTTA SVPDSVLDVF LKGNWSMQNP SPSCECSNEK
IKKMLPVCPA GAGGLPPPQR EQDTADILQN LTGRNISDYL VKTYAQIIGK SLKNKIWVNE
FRYGGFSLGA SSSLMLPPSH EVTDAIKQVK KVLELAQGSS GDRFLNSLSS FMKGLDTKNN
VKVWFNNKGW HAIASFLNVI NNAILRANLQ QGKNPSTYGI TAFNHPLNLT KQQLSEVALM
TTSVDVLVSI CVIFAMSFVP ASFVVFLIQE RVSKAKHLQF ISGVKPVIYW LANFVWDMCN
YIVPATLVII IFICFQQKSY VSSSNLPVLA LLLFLYGWSI TPLMYPASFV FKIPSTAYVV
LTSVNLFIGI NGSVATFVLE LFTNNKLNNI NDILKSVFLI FPHFCLGRGL IDMVKNQAMA
DALERFGENR FVSPLSWDLV GRNLFAMAVE GVVFFLITVL IQYRFFIKPR PVYAKLPPVN
DEDEDVNRER QRIISGGGQS DILEIKELTK IYRMKRKPAV DRICVGIPPG ECFGLLGVNG
AGKSSTFKML TGDTDVTGGE AFLKGNSILS NIQEVHQNMG YCPQFDAVNE LLTGREHLEF
FALLRGVPEK EVCKVGEWAI RKLGLVKYAE KYAGNYSGGN RRKLSTAIAL IGGPPVVFLD
EPTTGMDPKA RRFLWNCALS VIKEGRSVVL TSHSMEECEA LCTRMAIMVN GRFRCLGSVQ
HLKNRFGDGY TIVVRIAGAN PDLKPVEEFF GHAFPGSVLK EKHRNMLQYQ LPSSPSSLAR
IFSILSQNKK RLHIEDYSVS QTTLDQVFVN FAKDQSDDD
//
