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Database: UniProt
Entry: A0A091GC17_9AVES
LinkDB: A0A091GC17_9AVES
Original site: A0A091GC17_9AVES 
ID   A0A091GC17_9AVES        Unreviewed;      2957 AA.
AC   A0A091GC17;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 16.
DE   SubName: Full=Ryanodine receptor 2 {ECO:0000313|EMBL:KFO78856.1};
DE   Flags: Fragment;
GN   ORFNames=N303_00742 {ECO:0000313|EMBL:KFO78856.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO78856.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO78856.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO78856.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL447947; KFO78856.1; -; Genomic_DNA.
DR   RefSeq; XP_009562820.1; XM_009564525.1.
DR   GeneID; 104062467; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 2.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053760};
KW   Receptor {ECO:0000313|EMBL:KFO78856.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       33     88       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       94    151       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      159    216       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      419    617       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      833   1030       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1165   1370       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFO78856.1}.
FT   NON_TER    2957   2957       {ECO:0000313|EMBL:KFO78856.1}.
SQ   SEQUENCE   2957 AA;  334372 MW;  010F7210C9C21B23 CRC64;
     HLSYGNGSLH VDAAFQQTLW SVAPISSGSE VAQGYLIGGD VLRLLHGHMD ECLTVPSGEH
     GEEQRRTVHY EGGAVSIHAR SLWRLETLRV AWSGSHIRWG QPFRLRHITT GKYLSLLDDK
     TLLLTDKEKA DVKSTAFCFR SSKEKLDIGT RKEVDGMGAP EIKYGDSICF IQHVDTGLWL
     TYQSADAKSV RMGSVQRKAI MHHEGHMDDG LTLSRSQNEE SRTARVIRST VFLFNRFIRG
     LDALSKKVKS STVDLPIESV SLSLQDLIGY FHPPDEHLEH EDKQNRLRAL KNRQNLFQEE
     GMINLVLECI DRLNVYSSAA HFADVAGKEA GEAWKSILNS LYELLAALIR GNRKNCAQFS
     GSLDWLISRL ERLEASSGIL EVLHCVLVES PEALNIIKEG HIKSIICLLD KHGRNHKVLD
     VLCSLCVCHG VAVRSNQHLI CDNLLPGRDL LLQTRLVNHV SSMRPNIFLG ISEGSAQYRK
     WYYELMVDHL EPFVTAESTH LRVGWASTEG YSPYPGGGAE WGGNGVGDDL YSYGFDGLHL
     WSGCVARTVN SPNQHLLRTD DVISCCLDLS APSISFRING QPVQGMFENF NIDGLFFPVV
     SFSAGIKVRF LLGGRHGEFK FLPPPGYAPC FEAVLPKEKL KVEHSREYKQ DRNYTRDLLG
     PTISLSQAAF TPVPVDTSQI VLPPHLERIR EKLAENIHEL WVMNKIELGW QYGPVRDDNK
     RQHPCLVEFS KLPEQERNYN LQMSLETLKT LLALGCHVGI ADEHAEEKVK KMKLPKTYQL
     LSGYKPAPMD LSFIKLTPSQ EAMVDKLAEN AHNVWARDRI RQGWTYGIQQ DVKNRRNPRL
     VPYALLDDRT KKSNKDSLRE AVRTLLGYGY NLEAPDQDHA MRLDVCSGIM EKFRIFRTEK
     TYAVKTGKWY FEFEAVTAGD MRVGWTRPGC LPDQELGSDE EAFVFDGFKA QRWHQGNEHF
     GRSWLAGDVV GCMVDMNEHT MMFTLNGEIL LDDSGSELAF KDFEVGAGFL PVCSLGPSQV
     GRMNFGKDVS TLKYFTICGL QEGYEPFAVN TNRDITIWLS KRLPQFLPVP QNHEHIEVMR
     IDGTIDSCPC LKVTQKSFGS QNSKTDVLFF RLSMPIECAE VFSRTSAGGL PGSSLFGPKN
     DLDDYDADSD FEVLMKTAHG HLAPDRTERE KDATKPELNN HKDYVQEKPS RLKQRFMLRR
     TKPDYSTSHS ARLTEDVLAD DRDDYDYLMQ TSTYYYSVRI FPGQEPANVW VGWITSDFHQ
     YDTSFDLDRV RTVTVTLGDE KGKVHESIKR SNCYMVCAGE SMSPGQGRNN NGLEIGCLVD
     AASGLLTFTA NGKELGTYYQ VEPSTKLFPA VFAQATSPNI FQFELGRVKN VMPLSAGLFK
     SEHKNPISQC PPRLHVQFLT HVLWSRVPNH FLKVDVSRIS ERQGWMIQCL NPLQFMALHI
     PEENRTIDIL ELTEQEELLK FHYHTLRLYS AVCALGNNRV AHAMCSHVDE SQLLYAIENK
     YMPGLLRAGY YDLLIDIHLN TYATARLMMN NEFIVPMTDE TKSITLFPDE NKKHGLPGIG
     LSTSLRPRMQ FSSPSFVSIS SECFQFSPEF PLEILKAKTI EMLTEAVQEG SLHVRDPVGG
     STEFLFVPLI KLFYTLLIMG IFNNGDLKHI LQLIEPRVFK EAMSQEDETD FLEKEMNLDE
     LKSEEGEEET RGEQVPKEGL LQMKLPEPVK LQMCHLLQYL CDCQVRHRIE AIVAFSDDFV
     AKLQENQRFR YNEVMQALNM SAALTARKTK EFRSPPQEQI NMLLNFKDDK NDCPCPEEIR
     DQLLDFHEDL MTHCGIELDE DGTLDGNNDL TIRGRLLYLM EKVTYLKKKQ AEKPVDDDAK
     TSSTLQQLIS DTMVRWAQES VIEDPELVRA MFVLLHRQYD GIGGLVRALP KTYTINSVSV
     EDTINLLASL GQIRSLLSVR MGKEEEKLMI RGLGDIMNNK VFYQHPNLMR ALGMHETVME
     VMVNVLGGGE SKEITFPKMV ANCCRFLCYF CRISRQNQKA MFDHLSYLLE NSSVGLASPS
     MRGSTPLDVA AASVMDNNEL ALALREPDLE KVVRYLAGCG LQSCPLLISK GYPDIGWNPV
     EGERYLDFLR FAVFCNGESV EENANVVVRL LIRRPECFGP ALRGEGGNGL LAAMEEAIQI
     SEDPTRDGAS PSNGSSKTLE IEEQEDDTIH MGNAIMTFYA ALIDLLGRCA PEMHLIHAGK
     GEAIRIRSIL RSLIPLEDLV GVISIPFHMP TIAKDGTVVE PDMSAGFCPD HKAAMVLFLD
     RVYGIEDQDF LLHLLEVGFL PDLRAAASLD TAALSATDMA LALNRYLCTA VLPLLTRCAP
     LFAGTEHHAS LIDSLLHTVY RLSKGCSLTK AQRDSIEECL LSICGQLRPS MMQHLLRRLV
     FDVPLLNEHA KMPLKLLTNH YERCWKYYCL PGGWGNFGAA SEEELHLSRK LFWGIFDALS
     QKKYEQELFK LALPCLSAVA GALPPDYMES NYVNMMEKQS SMDSDGNFNP QPVDTSNITI
     PEKLEYFINK YAEHSHDKWS MEKFANGWTY GETYSESAKV QPLMKQYKLL SEKEKEIYRW
     PIKESLKTML AWGWRIERTR EGDSMALYNR TRRISQTSQI SVDTAHGYTP RAIDMSNVTL
     SRDLHAMAEM MAENYHNIWA KKKKMELEAK GGGNHPLLVP YDTLTAKEKA RDREKAQDIL
     KFLQINGYVV SRGLKDLELD TPSIEKRFAY SFLQQLIRYV DEAHQYILEF DGGSRGKGEH
     FPYEQEIKFF AKVVLPLIDQ YFKNHRLYFL SAASRPLSSG GHASNKEKEM VTSLFCKLGV
     LVRHRISLFG NDATSIVNCL HILGQTLDAR TVMKTGLESV KMALRAFLDN AAEDLEKTME
     NLKQGQFTHS RNQPKGVTQI INYTTVALLP VLSSLFEHIG QHQFGEDLIL EDVQVSCYRI
     LASLYALGTS KSIYVER
//
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