ID A0A091GC50_9AVES Unreviewed; 497 AA.
AC A0A091GC50;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Importin subunit alpha-1 {ECO:0000313|EMBL:KFO78901.1};
DE Flags: Fragment;
GN ORFNames=N303_00824 {ECO:0000313|EMBL:KFO78901.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO78901.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO78901.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO78901.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394}.
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DR EMBL; KL447967; KFO78901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GC50; -.
DR STRING; 55661.A0A091GC50; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF11; IMPORTIN SUBUNIT ALPHA-8; 1.
DR Pfam; PF00514; Arm; 7.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 9.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 4.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PROSITE-
KW ProRule:PRU00561}.
FT DOMAIN 1..53
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 111..154
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 154..182
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 249..291
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 291..333
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO78901.1"
FT NON_TER 497
FT /evidence="ECO:0000313|EMBL:KFO78901.1"
SQ SEQUENCE 497 AA; 55066 MW; 31457C21E1D34B2A CRC64;
NKSDERMKKF KNKGKDAAAL RRRRVEVNVE LRKAKKDEQI LKRRSISFRL LDENLNEERE
KRNEIIQLSL EEIVEAVNGN NAELQLQATQ ATRRMLSRQK DPLINEIIEL GIIPRLVEFL
IHADNPPLQF EAAWALTNIA SGTSDQTRAV VEGNAIPAFI SLLSSPHMHI SEQSVWALGN
IAGDGPLYRD ALIKCNVIPP LLALVSPATP VNNLPSLVFQ VGFLRNITWT LSNLCRNKNP
YPPLDAVKKM LPVLIRLIKH EDKDIISDSC WAVSYLTDGS NDRIQIVVDT GILPRLVELM
ASPELLVMTP ALRAIGNVVT GTDEQTQAAI DAGVLAVLPS LLRHGKPTIE KEAAWALSNI
AAGPSQQIQQ LIMCGLLPPL VELLDKGDFK AQKEAVWAVA NFTMGGTVEQ VVELVRSGVL
KPLLNLLLAK DSKTILVILD TISNLFRAAE KLGETERLCL LVEELDGLEK IEALQTHDNN
MVYKAALNII EKYFSGE
//
