ID A0A091GW60_BUCRH Unreviewed; 1425 AA.
AC A0A091GW60;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Pleckstrin homology domain-containing family G member 1 {ECO:0000313|EMBL:KFO86655.1};
GN ORFNames=N320_04033 {ECO:0000313|EMBL:KFO86655.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO86655.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO86655.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO86655.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL511785; KFO86655.1; -; Genomic_DNA.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd13243; PH_PLEKHG1_G2_G3; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR043324; PH_PLEKHG1_G2_G3.
DR PANTHER; PTHR45924; FI17866P1; 1.
DR PANTHER; PTHR45924:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054064}.
FT DOMAIN 116..296
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 320..419
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1132..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..1267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1311..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1315..1330
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1331..1352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1425 AA; 160777 MW; 74C7817788A5651C CRC64;
MDLSDSDRPV SFSSTSSSAS SRDSHCSFGS RMTLVSNSHL GLFNQDKEMG AIKLELVPAR
RFSSNKPRKN SPAEQEDPEK GIDKTLTMPR KAEPKGVSKN CAMSLVTEPT SPKLLYVDRV
VQEVLETERM YVQDLKSIVK DYLDCITDQT KLSLGTEERS ALFGNIRDIY HFNSELLQDL
ENCENDPVAI ADCFVSKSED FHIYTQYCTN YPRSVAVLTE CMRNKALAKF FRERQEALQH
SLPLGSYLLK PVQRILKYHL LLHEIENHLD KDTEGYDVVL DAIDTMQRVA WHINDMKRKH
EHAIRLQEIQ SLLTNWKGPD LTSYGELVLE GTFRIQRAKN ERTLFLFDKV LLITKKRDEM
FVYKAHILCG NLMLVEVIPK EPLSFSVFHY KNPKTQHTVQ AKSQQDKRLW ILHLKRLILE
NHPAKIPAKA KQAILEMDAI HHPGFHYSPE GETKSPYQPK EGTTPHRVRR KSEPSSRVHK
ALKSNGDRLM LLACFKSPQS SKDPSDEESS PLNTDLAFSC TARQPQSPRQ FSTPQSNSLI
MNILGGSTSV RNIWTDHQIR QALFPSRRPP YENEDDEDDY QMFVPSVSTS NASSAAAGER
RGSSGRPCSW HLGVVPQNET SSPTRHKIVR RASSAGESNT CTASARYKIG ERSSRREVKR
AEVSGMNAYP KSSEELTIDD IEHVYDNISY EDLKLMGLTR REETDRGPQR SARDSLYEAE
NKSSLDSPSK KRTGNQNRAS IRAGRDEILL SREAPTSSLD ELRIVEDNIY DTIPLPETAL
LNFKCDPLKS SKRRSFLALE KDFACCDNLR QFVSEESLQF SEDESPYHHV PVDNDYLSLV
DSSSNSDSLS HKSAADKLSE EVDEIWNDLE NYIKKNEEKT RDRHLAAFPV CKDDMQERLH
AGSTPELSKD VEYSLSTLSL PETPIFPNNV KPRAATISEA NLRLEDTTPC KENSFRSLNR
ASFSCEMPFV DSPYESANSV LSNAHAEGVE NDLAVVDKTK NRVFMMARQY SQKIKKANQL
LKVKSPEQEQ PASRQQKLKH RDLAAILEEK KQGGPAIGAR IAEYSQLYDQ IVFRESSPKV
QKEAWAAPQD PSAGRFSTPV AASAPCSQAT SECSRAEDWL LHSTYSNSEL ADFSPWPESQ
DPKSKSLFTE AGTKSNSRQL PSAGSVPSLQ LSNRLHVPAQ RWSAIISQPN KENLHQDHIY
NSLGRRVSNI KPQAYSRSQS SSSIVVSRSG ESIIYPNEMD KKKLHSNRNS RFSSHQTPRI
ASGCTGPDMR KQIPENCSDM ILQDSQKVLR VNRASPLTAQ MATQNYFSNF KDTAEGEGDD
DDDYVEIKSE DEGSDLEISQ NRTRKSDPKL RNTDAVPSEM LCGKTVSCTP AKSASSKHAL
TPYLTAYSDS DKLNDYLWRV PSPNQQNIVQ SLREKFQCLS SSSFA
//
