ID A0A091H0R7_BUCRH Unreviewed; 528 AA.
AC A0A091H0R7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Mitochondrial Rho GTPase 2 {ECO:0000256|ARBA:ARBA00040475};
DE AltName: Full=Ras homolog gene family member T2 {ECO:0000256|ARBA:ARBA00042451};
DE Flags: Fragment;
GN ORFNames=N320_08830 {ECO:0000313|EMBL:KFO88392.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO88392.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO88392.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO88392.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004200}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004200}.
CC -!- SIMILARITY: Belongs to the mitochondrial Rho GTPase family.
CC {ECO:0000256|ARBA:ARBA00007981}.
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DR EMBL; KL517142; KFO88392.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091H0R7; -.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR013566; EF_hand_assoc_1.
DR InterPro; IPR013567; EF_hand_assoc_2.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR020860; MIRO_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR003578; Small_GTPase_Rho.
DR PANTHER; PTHR24072:SF311; MITOCHONDRIAL RHO GTPASE 2; 1.
DR PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR Pfam; PF08355; EF_assoc_1; 1.
DR Pfam; PF08356; EF_assoc_2; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51423; MIRO; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..137
FT /note="Miro"
FT /evidence="ECO:0000259|PROSITE:PS51423"
FT DOMAIN 273..308
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 385..528
FT /note="Miro"
FT /evidence="ECO:0000259|PROSITE:PS51423"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO88392.1"
FT NON_TER 528
FT /evidence="ECO:0000313|EMBL:KFO88392.1"
SQ SEQUENCE 528 AA; 59303 MW; E37120BE5606D74F CRC64;
QVPPRAEEIT IPADVTPEKV PTHIVDYSES EQTEDELQEE IAKANVVCVV YDVTKEATIE
KIRTKWIPMV NGGVEKGSRI PIILVGNKSD LQLGSSMDVI LPIMNQFSEI ETCVECSAKN
LKNISELFYY AQKAVLHPTA PLYDPEEKQL KPACARALTR IFNLSDQDNN QILSDDELNY
FQKSCFGNPL APQALEDVKM VVWKNTTDGV QDNGLTLNGF LFLNTLFIQR GRHETTWTIL
RRFGYDDELE LTNDYLYPQF RVPAGCSTEL NHLGYQFLQR IFEKHDKDQD GALSPAELQN
FFSVFSCVPW GPELYNTVCT TDKGLLSLHG FLCQWTLVAY LDVRHCLECL GYLGYPILSE
QDSQTQALTV TREKRIDLEK GQTQRNVFLC KVLGARGAGK SAFLRAFLGR SLALWSRRPS
PRAGVRSSRP LWDGAVTGIL SPPAQLYEVS ADTKFAKPSD AACDVACFIY NPSDPRSFSY
CATIYKQHYM DSQIPCVFVA SKTDLPEASQ QPGLSPAEFC YKHCLPPP
//
