ID   A0A091H1Y6_BUCRH        Unreviewed;       897 AA.
AC   A0A091H1Y6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 25.
DE   SubName: Full=Protein FAM13B {ECO:0000313|EMBL:KFO88695.1};
GN   ORFNames=N320_05250 {ECO:0000313|EMBL:KFO88695.1};
OS   Buceros rhinoceros silvestris.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX   NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO88695.1, ECO:0000313|Proteomes:UP000054064};
RN   [1] {ECO:0000313|EMBL:KFO88695.1, ECO:0000313|Proteomes:UP000054064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO88695.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAM13 family.
CC       {ECO:0000256|ARBA:ARBA00007549}.
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DR   EMBL; KL518169; KFO88695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091H1Y6; -.
DR   Proteomes; UP000054064; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04393; RhoGAP_FAM13A1a; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR039102; FAM13.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR15904; FAM13; 1.
DR   PANTHER; PTHR15904:SF16; PROTEIN FAM13B; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054064}.
FT   DOMAIN          23..212
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          329..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          627..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          823..850
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        332..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        636..656
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   897 AA;  101964 MW;  9A04FE8E0B66E8B9 CRC64;
     MRKSSSPSLS NCNSVLANKI FGIPLDELQQ EGQPDNEVPF IVRHVVDYIE EHGGLEQEGL
     FQVNGNAETV EWLRQRYDNG EDVDLVKEAD VPSAISLLRF FLQELPEPVI PGSLHTHLMQ
     LSQDYNNEDE FGRKLRFLLQ QLPPVNYSLL KFLCKFLANV ASHHEEIWSA SSLAAVFGPD
     VFHIYTDVED LKEQEIVSRI MAGLLENYYE FFENEEEDFS STNDLSSITE QINDLLEEEE
     DVKLEQSEEL PEDGTEKPVE RPAVVHLDVT GSLSDSRSVT ASTSAHISPI SILPASADIL
     ERTIRAAVEQ HLFDLQSSLD NDLKHIQQHR PGCNNEAKNP TGDEEGSNNQ NDVIEDDTGS
     SENTGDCSEA LVCTDVASEA MKHDTVTEEE ESVQVRGRAS LFTVHEDLAF NMITMCLLFR
     QNSILLGGND RIPSEMFLDS SSKTCDLNAN TDSEVSGDGN VHVSEEALTV QVPRLDLKNV
     SDGDKWEDPF PAFKSWQEDS ESGEAQLSPQ AGRMTNHPLE EDCHPVLSHR SLDFGQSQRF
     LHDPETLDSS SKALSFVRTR RASFSSKDDK REDKTPYQLV KKLQKKIKQF EEQFEKEKNS
     KPSYSDIAAN PKVLKWMTEL TKLRKQIKDA KQRSSDGEFI PQSRPRSNTL PKSFGSSLDQ
     EDEENGDEMR LVQKEKKPTK EATLELILKR LKEKRVERCL PEDIKVTREE RNIVKPLYDR
     YRLVKQMLTR ASITPILGSP STKRRGQMLQ PIIEGETAHF FEEIKEEEEE SDGLSADLSD
     ILKTAAQTQP VLSPVENSES DVEDGQEKLT RDLRLSSTRA ASIPELLEQL WKARAEKKKL
     RKTLREFEEE FYQQNGRNVQ KEDRVPMLDE YREYKKIKAK LRLLEVLISK QDSSKSI
//