ID   A0A091H9A7_BUCRH        Unreviewed;       628 AA.
AC   A0A091H9A7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 24.
DE   SubName: Full=Rho GTPase-activating protein 18 {ECO:0000313|EMBL:KFO91285.1};
DE   Flags: Fragment;
GN   ORFNames=N320_06595 {ECO:0000313|EMBL:KFO91285.1};
OS   Buceros rhinoceros silvestris.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX   NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO91285.1, ECO:0000313|Proteomes:UP000054064};
RN   [1] {ECO:0000313|EMBL:KFO91285.1, ECO:0000313|Proteomes:UP000054064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO91285.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL526246; KFO91285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091H9A7; -.
DR   Proteomes; UP000054064; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04391; RhoGAP_ARHGAP18; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR   PANTHER; PTHR14963:SF6; RHO GTPASE-ACTIVATING PROTEIN 18; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054064}.
FT   DOMAIN          287..486
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO91285.1"
FT   NON_TER         628
FT                   /evidence="ECO:0000313|EMBL:KFO91285.1"
SQ   SEQUENCE   628 AA;  70869 MW;  B1AE06A01EDCE90E CRC64;
     RRSGQYTMNH DHSKKTPDGA SFDRSGSQDS LDELSMDDYW KELENIHETR GNNHEERVAL
     VVKEPDEGEL EEEWLKEAGL SNLFGESSGD SLESVFLSTL TRTQKAAVEK RVETVTQTMR
     KKNKQHQIPD VRDIFRLQND SKGKVCDGSE PSTVRASEDR NETQDGAKGP KFSLGPCEQK
     SPLEDMPFSD TDINLEIPFA EQAASLKDSS AGKMCKGGGG DTLLPNFRLP KDKTGTTKIG
     DLAPQDMKKV YSLALIELTA LYDILGTEFK QQKAVKIKTK DSGLFGVPLS VLLEQDQKKV
     PGTKIPLIFQ KLIAQIEEAT LETEGLLRIP GVATRVKSLC QELEAKFYEG TFSWENVKQH
     DAASLLKHFI RELPQPLLTV EYLKAFQDVQ NLPTKKQQLQ ALNLLVLLLP EANRDTLKVL
     LEFLQRVIDH RDKNKMTLKN VAVVMAPNIF TFHGFGSKTI EQSEFVMAAG TANVMRFMIR
     YQSLLWTIPK FIVNQVRKQN IESQKKEKKD KAVKKLLKKM AYDREKHEKQ EKTTNDADVP
     QGVIRVQAPH LSRVSMAIQL TEELKAGDIV ARFLSQRSGN VPALKKEEVF LYEIGGNIGE
     RCLDGDTYMK DLYQLNPNAE WVIKSKQS
//