ID   A0A091HI63_CALAN        Unreviewed;       755 AA.
AC   A0A091HI63;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=RUN and TBC1 domain-containing protein 3 {ECO:0000256|ARBA:ARBA00030864};
DE   Flags: Fragment;
GN   ORFNames=N300_11568 {ECO:0000313|EMBL:KFO95988.1};
OS   Calypte anna (Anna's hummingbird) (Archilochus anna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC   Trochilidae; Calypte.
OX   NCBI_TaxID=9244 {ECO:0000313|EMBL:KFO95988.1, ECO:0000313|Proteomes:UP000054308};
RN   [1] {ECO:0000313|EMBL:KFO95988.1, ECO:0000313|Proteomes:UP000054308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N300 {ECO:0000313|EMBL:KFO95988.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the small G protein signaling modulator family.
CC       {ECO:0000256|ARBA:ARBA00006296}.
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DR   EMBL; KL217503; KFO95988.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091HI63; -.
DR   STRING; 9244.A0A091HI63; -.
DR   Proteomes; UP000054308; Unassembled WGS sequence.
DR   CDD; cd17688; RUN_SGSM3; 1.
DR   CDD; cd11813; SH3_SGSM3; 1.
DR   Gene3D; 1.20.58.900; -; 1.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   InterPro; IPR035833; SGSM3_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR   PANTHER; PTHR47219:SF19; RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   Pfam; PF02759; RUN; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00593; RUN; 1.
DR   SMART; SM00326; SH3; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50826; RUN; 1.
DR   PROSITE; PS50002; SH3; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          113..308
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   DOMAIN          484..543
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          559..722
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO95988.1"
FT   NON_TER         755
FT                   /evidence="ECO:0000313|EMBL:KFO95988.1"
SQ   SEQUENCE   755 AA;  86525 MW;  0007EF9A2BE96C90 CRC64;
     GHHTPSAGGP FSALTPSIWP QEILAKYTQK EESIEQLEFH YDEFGFRVDK EDGAEPNSSK
     LLGVPLTEEP QQRLKWQAHL EFTHNHDVGD LTWDKIEVTL PHSDKLRSLV LAGIPHSMRP
     QLWMRLSGAL QKKRSSEMSY RDIVKNSSND ETIAAKQIEK DLLRTMPSNA CFSNMNSIGV
     PRLRRILRGL AWLYPDIGYC QGTGMVTCFQ KEDVDHLETG PALHVRKLGI IEELVPASYF
     STTLMGVQTD QRVLRQLIVQ YLPRLDKLLQ EHDIELSLIT LHWFLTSFAS VVHIKLLLRI
     WDLFFYQGSL VLFQLTLGML SLKEDELIQS EYSASIFIML SDIPSQMEDA DVLLREAMRV
     AGSLTDVAVE TQRRKHLAYL IADQGQLLNS STTVNNLSKV VRRRTQRRKS GITSLLFGDD
     DLEALKAKNI KQTELVADLR EAILQVARHF QCVDPKNCSI DLTPDYSMES HQQDHENYVA
     CSRTRRRRAK ALLDFERHDD DELGFRKNDI ITIISQKDEH CWVGELNGLR GWFPAKFVEI
     LDERSKEYSI AGDDSVTEGV TDLVRGTLCP ALKSIFEHGL KKPSLLGGAC HPWLFIEEAA
     SREVERDFDS VYSRLVLCKT YRLDEDGKVL TPEELLYRAV QAVNMTHDAA HAQMDVKLRS
     LICVGLNEQV LHLWLEVLCS SLQTVEKWFH PWSFLRSPGW VQIKCELRVL CKFAFSLSQD
     WELPIKREEK EKKPLKEGVQ DMLVKHHLFS WDIDG
//