ID A0A091HYI0_BUCRH Unreviewed; 596 AA.
AC A0A091HYI0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Carnitine O-acetyltransferase {ECO:0000313|EMBL:KFO92298.1};
DE Flags: Fragment;
GN ORFNames=N320_04247 {ECO:0000313|EMBL:KFO92298.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO92298.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO92298.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO92298.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR EMBL; KL529422; KFO92298.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091HYI0; -.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF50; CARNITINE O-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000054064};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 8..579
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 313
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
FT BINDING 389
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 393..400
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 422
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 424
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 426
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 435
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 474
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 525
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO92298.1"
FT NON_TER 596
FT /evidence="ECO:0000313|EMBL:KFO92298.1"
SQ SEQUENCE 596 AA; 67685 MW; CBD496C64B128034 CRC64;
YQQALPPLPV PPLQQTLDRY LLALQPIISE EELNHTQELV TEFRKPGGVG ERLQKGLERR
AKKTENWLSD WWLKTAYLEY RLPVVVHSSP GVVLPKQDFL DRQGQLRFAA KLIEGILDFK
TMIDNETLPV EYMGGKPLCM NQYYQILSSC RIPGPKRDTI VNYAKGKKQS RHITVVHNFQ
FFELDVYNSD GSPLTTDQLF AQLEKIWNTS LQTNKEPVGI LTTNHRNSWA KAYNNLLKDK
TNKESVRSIE KSICVVCLDA PMPRVSEDIY RSRVAAQMLH GGGSRLNSGN RWFDKTLQFI
IAEDGSCGLV YEHAPAEGPP IVALLDHIVE YTKKPELVRS PMIPLPMPKK LRFNITPEIK
NDIEKAKQNL NIMVEDLDVK VSVFHQFGKN FPKSEKISPD AFIQLALQLA YYRMYGHACA
TYESASLRMF RLGRTDTIRS NSVDSLKFVQ AMDSPDKSDQ EKTHLLRRAT QAHREYTDMA
IRGNAIDRHL LGLKLQAVED LVSIPELFMD TAYAVAMHFN LSTSQVPAKT DCVMCFGPVV
PDGYGVCYNP MDEHINFAVS AFNSCADTNA ARMTHYLEKA LLDMRVLLQS TPKSKL
//
