ID   A0A091I2Q8_CALAN        Unreviewed;       836 AA.
AC   A0A091I2Q8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=N300_05434 {ECO:0000313|EMBL:KFP01738.1};
OS   Calypte anna (Anna's hummingbird) (Archilochus anna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC   Trochilidae; Calypte.
OX   NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP01738.1, ECO:0000313|Proteomes:UP000054308};
RN   [1] {ECO:0000313|EMBL:KFP01738.1, ECO:0000313|Proteomes:UP000054308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP01738.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC       multimeric enzyme that catalyzes the translocation of protons across
CC       the membranes. Required for assembly and activity of the V-ATPase.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KL218042; KFP01738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091I2Q8; -.
DR   STRING; 9244.A0A091I2Q8; -.
DR   Proteomes; UP000054308; Unassembled WGS sequence.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629:SF26; V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 4; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW   ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        401..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        445..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        543..564
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        570..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        640..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        768..792
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   REGION          671..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          93..120
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   836 AA;  95809 MW;  D446904C6A71316F CRC64;
     MGSFFRSEEM SLTQMFLQVE ASYCCIAELG ELGLVQFRDL NANVNSFQRK FVTEVRRCES
     LERILRYLEK EIGDNVETVK PETYPETPLP WEITDMETVL QKLEADLLEA NHNQQTLRQN
     LLGLIELKHL LKKTQDFFVT ETSLTDDFFG GDSSGLLELK TTTITAKLGF IAGVIRREKM
     INFENILRRV SRGNIYLRYT EMDTPLEDPV TREEVRKNVF IIFYQGEQLK QKIVSICAGF
     RATTYPCPES AADRQERLYG VNTRIEDLNT VMFQTEFHRQ TLLQDAAAGL WLWWIKVKKI
     KAVYHILNCC NIDVTQQCII AEMWFPVADS ARIKAALQQG MERSGSTIAP ILTAVRTRVA
     PPTFNRTNKF TAGFQNIVDA YGVGNYMELN PAPYTIITFP FLFAVMFGDC GHGAIMLGVA
     LWMVINEKSL IAQKSANEIW NTFFSGRYLI LLMGIFSVYT GFIYNDCFSK SFNIFGSSWH
     IIPMFKNNTW NKNVLLHNTM LELDPAVPGV YSGNPYPFGI DPIWNIASNK LTFLNSYKMK
     MSIVIGIVHM VFGVILGLFN HIYFKRYINI ILQFIPEMIF MISLFGYLVF MIIFKWCHFD
     VHSSSIAPSI LIHFINMFLF NYSDTSNAPL YEHQKEVQTF LVIFALIAVP WMLLIKPFIL
     RANHQRAERM VRGSPAREND IGDPENNHSK KASHGHLNVD HEEHEEDEEF NFGDICVHQA
     IHTIEYCLGC ISNTASYLRL WALSLAHAQL SEVLWNMVMH NGFSSGSWAG LIAIFIVFAA
     FAVLTVAILL VMEGLSAFLH ALRLHWVEFQ NKFYMGAGHK FCPFSFKRII DGTTEE
//