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Database: UniProt
Entry: A0A091IGB7_CALAN
LinkDB: A0A091IGB7_CALAN
Original site: A0A091IGB7_CALAN 
ID   A0A091IGB7_CALAN        Unreviewed;      1108 AA.
AC   A0A091IGB7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   10-MAY-2017, entry version 18.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N300_07949 {ECO:0000313|EMBL:KFP07644.1};
OS   Calypte anna (Anna's hummingbird) (Archilochus anna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Trochiliformes; Trochilidae; Calypte.
OX   NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP07644.1, ECO:0000313|Proteomes:UP000054308};
RN   [1] {ECO:0000313|EMBL:KFP07644.1, ECO:0000313|Proteomes:UP000054308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP07644.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
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DR   EMBL; KL218730; KFP07644.1; -; Genomic_DNA.
DR   Proteomes; UP000054308; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001696; Na_channel_asu.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   Pfam; PF00520; Ion_trans; 3.
DR   Pfam; PF00612; IQ; 1.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   PRINTS; PR00170; NACHANNEL.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000054308};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFP07644.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     20     44       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     74     94       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    106    129       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    337    355       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    376    398       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    404    424       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    453    479       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    577    600       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    658    676       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    688    706       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    718    738       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    775    803       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    877    902       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN        1    133       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      143    330       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN      335    608       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      657    912       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFP07644.1}.
FT   NON_TER    1108   1108       {ECO:0000313|EMBL:KFP07644.1}.
SQ   SEQUENCE   1108 AA;  126329 MW;  F31374E0E7AADCCC CRC64;
     LRVFKLAKSW PTLNMLIKII GNSVGALGNL TLVLAIIVFI FAVVGMQLFG KSYIECVCKI
     SQDCTLPRWH MNDFFHSFLI VFRILCGEWI ETMWDCMEVA GQTMCLIVFM MVMVIGNLVV
     LNLFLALLLS SFSADSLAAS DDDGELNNLQ IAIGRITRGI QFAKNFLLTR LRRLWKGKKV
     APEEEQEHSK RENSVLNHLD GGQELKPDHP DGIPGKEHFF MDELDHMNFI TNPNLTVQVP
     IASEEFSLTC ISHPLPLQIP LTSDNASSLC STVDYKPPDP EEEEVAEVAE ESNEPEECFT
     EACVKRFPCL YVDITTEKGR MWWNLRKTCF TIVEHDWFET FIVFMILLSS GALAFEDIYI
     EQRRVIRTIL EYADKVFSYI FVIEMLLKWV AYGFKVYFTN AWCWLDFLIV DVSLVSLTAN
     WLGYSELGAI KSLRTLRALR PLRALSRFEG MRVVVNALLG AIPSIMNVLL VCLIFWLIFS
     IMGVNLFAGK YYRCVNTTTG ELFEISVVNN KSDCMALLHT NEVRWVNVKV NFDNVGLGYL
     SLLQVATFKG WMDIMYAAVD SREIEEQPMY EINLYMYIYF VIFIIFGAFF TLNLFIGVII
     DNFNQQKKKI SKDIFMTEEQ KKYYNAMKKL GSKKPQKPIP KPANKFQARV FEFVTKQVFD
     ITIMILICLN MVTMMVETDD QSELKTAVLY KINLVFIVIF TGECVLKMFA LRHYFFTIGW
     NIFDFVVVIL SILGIVLSDI IEKYFVSPTL FRVIRLARIG RVLRLIRGAK GIRTLLFALM
     MSLPALFNIG LLLFLVMFIY SIFGMSNFAY VKKESGIDDI FNFETFGNSM ICLFQITTSA
     GWDGLLNPIL NSGPPDCDPD LENPGSSVKG NCGNPSIGIF FFCSYIIISF LIVVNMYIAI
     ILENFSVATE ESSEPLCEDD FEMFYETWEK FDPDATQFIA YSTLSDFVDT LQEPLKIPKP
     NKIKLITMDL PMVAGDKIHC LDILFALTKE VLGDSGEMDA LKATMEEKFM AANPSKVSYE
     PITTTLKRKH EEVCAIKIQR AFRRYLLRRS VKQASYMYRQ GKDEDEPHGE APEKEGLIAT
     KMQEMYGNSG TGLEEGSAFG LEPVPSSE
//
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