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Database: UniProt
Entry: A0A091KKQ2_9GRUI
LinkDB: A0A091KKQ2_9GRUI
Original site: A0A091KKQ2_9GRUI 
ID   A0A091KKQ2_9GRUI        Unreviewed;      1546 AA.
AC   A0A091KKQ2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   07-JUN-2017, entry version 19.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N324_05778 {ECO:0000313|EMBL:KFP39790.1};
OS   Chlamydotis macqueenii (Macqueen's bustard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX   NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP39790.1, ECO:0000313|Proteomes:UP000053330};
RN   [1] {ECO:0000313|EMBL:KFP39790.1, ECO:0000313|Proteomes:UP000053330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP39790.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
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DR   EMBL; KK744623; KFP39790.1; -; Genomic_DNA.
DR   Proteomes; UP000053330; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR008051; Na_channel_a1su.
DR   InterPro; IPR001696; Na_channel_asu.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR024583; Na_trans_cytopl.
DR   Pfam; PF00520; Ion_trans; 3.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   Pfam; PF11933; Na_trans_cytopl; 1.
DR   PRINTS; PR00170; NACHANNEL.
DR   PRINTS; PR01664; NACHANNEL1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053330};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFP39790.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    305    329       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    341    362       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    424    452       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    511    537       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    763    781       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    802    821       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    833    856       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    877    905       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1004   1027       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1085   1103       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1115   1133       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1145   1165       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1202   1230       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1306   1329       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN       54    260       Na_trans_cytopl. {ECO:0000259|Pfam:
FT                                PF11933}.
FT   DOMAIN      314    541       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      551    757       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN      761   1035       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1084   1339       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFP39790.1}.
FT   NON_TER    1546   1546       {ECO:0000313|EMBL:KFP39790.1}.
SQ   SEQUENCE   1546 AA;  175398 MW;  073F2E102787AC0D CRC64;
     QAAAVAATAV TASAESREPS AAGEGGGLSE SSSDASKLSS KSAKERRNRR KKRKQKEQSG
     GEEKDEDEFH KSESEESIRR KGFRLSIEGN RLTYEKKYSS PHQSLLSIRG SLFSPRRNSR
     TSLFSFRGRA KDIGSENDFA DDEHSTFEDN DSRRDSLFVP RRHGERRNSN ISQASRSSRM
     LAVFPVNGKM HSTVDCNGVV SLVGGPSVPT SPVGQLLPEV IIDKPATDDN GTTTETEMRK
     RISSSFHVSM DFLEDPAAMS IASILTNTVE ELEESRQKCP PCWYKFANIF LIWDCSPHWL
     KVKHIVNLVV MDPFVDLAIT ICIVLNTLFM AMEHYPMTDE FNNVLSVGNL VFTGIFTAEM
     FLKIIAMDPY YYFQEGWNIF DGFIVTLSLV ELGLADVEGL SVLRSFRLLR VFKLAKSWPT
     LNMLIKIIGN SVGALGNLTL VLAIIVFIFA VVGMQLFGKN YKECVCKIAS DCVLPRWHMQ
     DFFHSFLIVF RVLCGEWIET MWDCMEVAGQ AMCLTVFMMV MVIGNLVVLN LFLALLLSSF
     SADNLAVTDD DNEMNNLQIA VARMQKGIDY VKRKAREFIQ KAFVKKQKAL DEIKPLEDLN
     NKNSCISNHT TVELSKDHDY IKDANGTTSG IGTGSSVEKY IIDESDYMSF INNPSLTVTV
     PIAVGESDFE NLNTEEFSSE SDLEESKEKL NSSSSSEGST VDIGLPAEEQ PEAEPEEAQE
     PEACFTEGCV QRFKCCQVSI EEGRGKQWWN LRKTCFKIVE HNWFETFIVF MILLSSGALA
     FEDIYIEQRK TIKTMLEYAD KVFTYIFILE MLLKWVAYGY QTYFTNAWCW LDFLIVDVSL
     VSLTANALGY SELGAIKSLR TLRALRPLRA LSRFEGMRVV VNALLGAIPS IMNVLLVCLI
     FWLIFSIMGV NLFAGKFYYC VNTTTDERFE VDQINNFSQC EELIKNNQSA RWKNVKVNFD
     NVGFGYLSLL QVATFKGWMD IMYAAIDSRE VLQQPKYEDN LYMYLYFVIF IIFGSFFTLN
     LFIGVIIDNF NQQKKKISQD IFMTEEQKKY YNAMKKLGSK KPQKPIPRPG NKFQGMVFDF
     VTQQVFDISI MILICLNMVT MMVETDDQSK EMETILYWIN LVFIVLFTGE CVLKLISLRH
     YYFTIGWNIF DFVVVILSIV GMFLAEMIEK YFVSPTLFRV IRLDRIGRIL RLIKGAKGIR
     TLLFALMMSL PALFNIGLLL FLVMFIYAIF GMSNFAYVKR EVGIDDMFNF ETFGNSMICL
     FQITTSAGWD GLLAPILNSG EPDCDPNKAH PGSSVKGDCG NPSVGIFFFV SYIIISFLVV
     VNMYIAVILE NFGVATEESA EPLSEDDFEM FYEVWEKFDP DATQFMEFEK LSDFAAALEP
     PLHLPKPNKV QLIAMDLPMV SGDRIHCLDI LFAFTKRVLG ESGEMDALRI QMEDRFMASN
     PSKASYEPIT TTLKRKQEEV SAVIIQRAYR RHLLKRTVKQ ASFIYNKNKT EGGASQGMKG
     EILIDKLNEN SFTEKTDITA STAVCPPSYD RVTRLVKEKH EKEDKD
//
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