ID A0A091KN68_9GRUI Unreviewed; 371 AA.
AC A0A091KN68;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=[Arg8]-vasotocin receptor {ECO:0000313|EMBL:KFP40680.1};
GN ORFNames=N324_11859 {ECO:0000313|EMBL:KFP40680.1};
OS Chlamydotis macqueenii (Macqueen's bustard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP40680.1, ECO:0000313|Proteomes:UP000053330};
RN [1] {ECO:0000313|EMBL:KFP40680.1, ECO:0000313|Proteomes:UP000053330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP40680.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC Vasopressin/oxytocin receptor subfamily.
CC {ECO:0000256|RuleBase:RU046427}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU046427}.
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DR EMBL; KK747452; KFP40680.1; -; Genomic_DNA.
DR RefSeq; XP_010116071.1; XM_010117769.1.
DR AlphaFoldDB; A0A091KN68; -.
DR GeneID; 104477615; -.
DR KEGG; cmac:104477615; -.
DR OrthoDB; 2879183at2759; -.
DR Proteomes; UP000053330; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; ISS:AgBase.
DR GO; GO:0004930; F:G protein-coupled receptor activity; ISS:AgBase.
DR GO; GO:0017046; F:peptide hormone binding; ISS:AgBase.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; ISS:AgBase.
DR GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
DR GO; GO:0019722; P:calcium-mediated signaling; ISS:AgBase.
DR CDD; cd15388; 7tmA_V2R; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001817; Vasoprsn_rcpt.
DR PANTHER; PTHR24241:SF74; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00896; VASOPRESSINR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU046427};
KW Glycoprotein {ECO:0000256|RuleBase:RU046427};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU046427};
KW Receptor {ECO:0000256|RuleBase:RU046427, ECO:0000313|EMBL:KFP40680.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW Transducer {ECO:0000256|RuleBase:RU046427};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU046427};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU046427}.
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 118..136
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 157..181
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 206..225
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 274..291
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT DOMAIN 60..327
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 42598 MW; 9D37E2E75BC7BE48 CRC64;
MKNFSFPMQD NTHRTESPAP HRFQSLTNQS DSVGRPERDE QLAQVEIAVL GVIFLTASVG
NFILILVLWR RRKKLSRMYI FMLHLSVADL VVAFFQVLPQ LIWDITDVFI GPDFLCRIIK
YLQLLGMFAS TYMIVVMTVD RYQAVCYPMV TFQKKRALWN IPICTSWSIA LVLSLPQVFI
FSKTEISPGI FECWGEFIQP WGPRAYVTWI FVVIFFIPSA ILITCQVKIC RIIKRNIYVK
KQNEYEVTNQ KQVLPSRASS VNCISKAMIK TVKMTVVTVV AYVLCWSPFF IAQLWSVWFP
SVVTEGSAFT IIMLLGNLNS CTNPWIYMYF CGHIPYCTNK QLENSPAQEE SVITGSIHLV
DRDPEENSTS A
//
