ID A0A091LJA8_CATAU Unreviewed; 338 AA.
AC A0A091LJA8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=Bone morphogenetic protein 15 {ECO:0000313|EMBL:KFP57058.1};
GN ORFNames=N323_04751 {ECO:0000313|EMBL:KFP57058.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP57058.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP57058.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP57058.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KL328061; KFP57058.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LJA8; -.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF22; BONE MORPHOGENETIC PROTEIN 15; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..338
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001876476"
FT DOMAIN 211..338
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 338 AA; 37436 MW; 5BE522F615694B98 CRC64;
MALLHPFTSL LLLLAMPLSW AANQSMLPPG SLPAVPPLPL LQALQARAPG SWGGPASGQP
LRYMLDLYRR AADREGRPRH GRSLDTNTVR LVQASSHGGQ PWAGRWYMQP LTYRLEGQPE
AEHLLRATVV YLPSLPLARG RLLCALELVA TTKAPGVLLS PAAHPRHGWA AADVTPYLLP
GNGRPRAPPS PRLYLNDTRA GLAPPAAEPH RHRRDTGMLA HDLPGYLREQ GGEKSDCSLR
PFPVSFAQLG WDHWIIAPHR YNPRYCKGAC PRLLRSDYHA PNHAVVQSFV HQLVDANVPW
PSCVPYRYSP ISVLMIERDG GILYKEYENM IAESCTCR
//
