ID A0A091LR34_CARIC Unreviewed; 621 AA.
AC A0A091LR34;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Proprotein convertase subtilisin/kexin type 6 {ECO:0000313|EMBL:KFP61958.1};
DE Flags: Fragment;
GN ORFNames=N322_08822 {ECO:0000313|EMBL:KFP61958.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP61958.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP61958.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP61958.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KK507776; KFP61958.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LR34; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00064; FU; 4.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR032778; GF_recep_IV.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR010909; PLAC.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR PANTHER; PTHR42884:SF8; PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6; 1.
DR Pfam; PF14843; GF_recep_IV; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00261; FU; 5.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 164..304
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT DOMAIN 583..621
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP61958.1"
FT NON_TER 621
FT /evidence="ECO:0000313|EMBL:KFP61958.1"
SQ SEQUENCE 621 AA; 68083 MW; CAEF88A265674F91 CRC64;
QGRRGLGSIF VWASGNGGRE GDYCSCDGYT HSIYTISISS TTENGYKPWY LEECASTLAT
TYSSGAFYER KIVTTDLRHR CTDGHTGTSV SAPMVAGIIA LALEANPLLT WRDVQHLLVK
TSRPVHLRAA DWKTNGAGHK VSHLYGFGLV DADAIVVEAK KWKAVPPQHV CVGSLDRVPK
YIRADHVLRA STLSSACAEH RDQHVIYLEH VVVRLSISHP RRGDLQISLV SPAGTRSQLL
ARRLFDNSNE GFKGWEFMTV HCWGERAAGE WTLEIHDTPS QVRNPAVQGK LKEWSLLFYG
TAEHPYAGLG GPQPRGRMLE VPASEMEPSR AAFLQSQVEV VEEEEEYAGP CHPECGDQGC
DGPNADQCLN CIHYSLGSVK TGRMCVSSCP AGFFGDKGAR RCRRCYKGCE RCVGRGPTQC
TACKRSLYHH QEMSTCVVLC PAGFYTEERQ KRCLKCHQSC KKCVGEADKC TACKDGFSLA
GESCVPECQP AMYLSREPRR CETCPTSTGP GEEDCAPCAP EPPAPHWRCV PACREGFYPA
DSHGLPNKVC KRCDDHCSAC EGSGGNCLKC KEGFSLLGGS CVTNETCTNA DKTFCEMVKS
NKLCEKKLFV QFCCQTCLMA G
//
