ID A0A091M0V1_CARIC Unreviewed; 437 AA.
AC A0A091M0V1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=phosphatidylinositol N-acetylglucosaminyltransferase {ECO:0000256|ARBA:ARBA00012420};
DE EC=2.4.1.198 {ECO:0000256|ARBA:ARBA00012420};
DE AltName: Full=GlcNAc-PI synthesis protein {ECO:0000256|ARBA:ARBA00032160};
DE Flags: Fragment;
GN ORFNames=N322_11918 {ECO:0000313|EMBL:KFP64259.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP64259.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP64259.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP64259.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
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DR EMBL; KK514451; KFP64259.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091M0V1; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0000506; C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; IEA:InterPro.
DR GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03796; GT4_PIG-A-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR039507; PIG-A/GPI3.
DR InterPro; IPR013234; PIGA_GPI_anchor_biosynthesis.
DR PANTHER; PTHR45871; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN; 1.
DR PANTHER; PTHR45871:SF1; PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR Pfam; PF08288; PIGA; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:KFP64259.1};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFP64259.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..122
FT /note="PIGA GPI anchor biosynthesis"
FT /evidence="ECO:0000259|Pfam:PF08288"
FT DOMAIN 180..325
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP64259.1"
FT NON_TER 437
FT /evidence="ECO:0000313|EMBL:KFP64259.1"
SQ SEQUENCE 437 AA; 49002 MW; F955A148708A6010 CRC64;
CMVSDFFYPN MGGVESHVYQ LSQCLIERGH KVLVVTHAYG HRKGGRYLTN GLKVYYLPLK
VMYNQSTFHS LPLLRYILVR ERVTIVHAHS SFSAMAHDAL FHAKTMGLRT VFTDHSLFGF
ADVSSVLTNK LLTVSLCDTN HIICVSYTSK ENTVLRAALD PRIVSVIPNA VDPTDFTPDP
SRRDDSTITI VVVSRLVYRK GIDLLSGIIP ELCQKYPELH FLVGGEGPKR IILEEVRERY
QLHDRVRLLG ALEHQDVRNV LVQGHIFLNT SLTEAFCMAI VEAASCGLQV VSTRVGGIPE
VLPENLIILC EPSVKSLCGG LEKAIAQLRS GTLPSPETVH NQVKTFYTWR NVAERTEKVY
DRVADEVVLP MDERLDRLMS HCGPVTGCIF ALFAVLNFLF LAFLRWMTPD SIIDVAIDAT
GPKGAWTKQY FLGKKRK
//
