ID   A0A091MAN2_CARIC        Unreviewed;      1035 AA.
AC   A0A091MAN2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   13-SEP-2023, entry version 32.
DE   SubName: Full=Pappalysin-1 {ECO:0000313|EMBL:KFP68576.1};
DE   Flags: Fragment;
GN   ORFNames=N322_11424 {ECO:0000313|EMBL:KFP68576.1};
OS   Cariama cristata (Red-legged seriema).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX   NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP68576.1, ECO:0000313|Proteomes:UP000054116};
RN   [1] {ECO:0000313|EMBL:KFP68576.1, ECO:0000313|Proteomes:UP000054116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP68576.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M43B family.
CC       {ECO:0000256|ARBA:ARBA00008721}.
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DR   EMBL; KK527271; KFP68576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091MAN2; -.
DR   MEROPS; M43.004; -.
DR   Proteomes; UP000054116; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   CDD; cd04275; ZnMc_pappalysin_like; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 4.10.470.20; -; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006558; LamG-like.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR011936; Myxo_disulph_rpt.
DR   InterPro; IPR000800; Notch_dom.
DR   InterPro; IPR043543; PAPPA/PAPPA2.
DR   InterPro; IPR008754; Peptidase_M43.
DR   NCBIfam; TIGR02232; myxo_disulf_rpt; 1.
DR   PANTHER; PTHR46130; LAMGL DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46130:SF2; PAPPALYSIN-1; 1.
DR   Pfam; PF13385; Laminin_G_3; 1.
DR   Pfam; PF05572; Peptidase_M43; 1.
DR   SMART; SM00560; LamGL; 1.
DR   SMART; SM00004; NL; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          97..246
FT                   /note="LamG-like jellyroll fold"
FT                   /evidence="ECO:0000259|SMART:SM00560"
FT   DOMAIN          381..423
FT                   /note="LNR"
FT                   /evidence="ECO:0000259|SMART:SM00004"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..70
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP68576.1"
FT   NON_TER         1035
FT                   /evidence="ECO:0000313|EMBL:KFP68576.1"
SQ   SEQUENCE   1035 AA;  115721 MW;  B1BD49370A4E1FC1 CRC64;
     TALASGPECG MDERSRRARR DTRHSRQLRY SAPGTCATRL ARGRRSTAGL EPGHVPRRRQ
     QREVKEEEES LTPSRALYFS GQGDQLRLKA DIELPRDAFT LQVWLKAEGG QRSPAVIAGL
     YDKCSYTSRD RGWVLGINTV SDQGNRDPRY FFSLKTDRAR KVTTIAAHRS YLPNQWVHLA
     ATYDGHLMKL YVNGAQVATS GEQVGSIFSL LTLKCKVLMV GGNALNQNYR GYVEHFSLWR
     TARSQKEILL DMGQAIHRQD MPLPQLVLQD SLLNVKNTWS PMKDGSSPQS KFSYHHGYLL
     DTSLDPPLCG QTVCDNTDVI ASYNKLPSFR RNKIVRYRVV NLYDDKHQNP TVSQQQIEFQ
     HQHLNEAFSR YNITWELEVL EVKNSSLRHR LILANCDISK IGDENCDPEC NHTLTGYDGG
     DCRHVRHTLF NKKKQNGVCD MDCNYERYNF DGGECCNPEI TEVTKTCFDP YSPYRAYLDV
     NELKNILKLD GSTHLNIFFA NSSEEELAGV ATWPWDKEAL MHLGGIVLNP SFYGIPGHTH
     TMIHEIGHSL GLYHVFRGIS EILSCSDPCM ETEPSFETGD LCSDTNPAPK HKLCGDPGPG
     NDTCGFHNFL NTPFSNFMSY ADDDCTDSFT PNQVARMHCY LDLVYQSWQP TKKPAPIAIA
     PQIVARTSAS VTLEWFPPID GHFFEREVGS ACDLCAEGRV LVQYAFSASS PMPCDPSGHW
     SPREAEGHPD VEQPCKSSVR TWSPNSAVNQ HTVPPACPEP QGCYLQLEFH YPLTPESLTV
     WVTFVSPDWD SSGAVNDIKL LTISGKNISL GPQNVFCDIP LTIKLDAGQV GEEVYGIQIY
     TLDEHLEIDA AMLSSVPYST LCADCKPIQY KVVRDPPFQS GSPVVISNLN RRFVDTELSD
     RTTYTYQVVI VSGTEESEPS PALVYISGSG YCGDGIIQID LGEECDDMNK INGDGCSLFC
     LQELSFNCID EPSRCYFHDG DGVCEEFEQM TSIKDCGVYT PKGFLDQWAS NVSVSHHSDQ
     QCPGWVVIGQ PAATQ
//