ID A0A091MRB0_CARIC Unreviewed; 3109 AA.
AC A0A091MRB0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Protocadherin Fat 3 {ECO:0000313|EMBL:KFP64080.1};
DE Flags: Fragment;
GN ORFNames=N322_12458 {ECO:0000313|EMBL:KFP64080.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP64080.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP64080.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP64080.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KK513888; KFP64080.1; -; Genomic_DNA.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 21.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 21.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24025:SF23; CADHERIN-4; 1.
DR PANTHER; PTHR24025; DESMOGLEIN FAMILY MEMBER; 1.
DR Pfam; PF00028; Cadherin; 19.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF02210; Laminin_G_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 21.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49313; Cadherin-like; 21.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00232; CADHERIN_1; 10.
DR PROSITE; PS50268; CADHERIN_2; 21.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2708..2728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..121
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 122..226
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 227..324
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 325..438
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 454..541
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 538..639
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 640..741
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 742..842
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 843..949
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 950..1051
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1052..1155
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1156..1261
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1262..1367
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1368..1477
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1478..1582
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1583..1684
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1685..1789
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1790..1894
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1895..1999
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2000..2104
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2115..2206
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2348..2386
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2388..2571
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2574..2611
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2613..2649
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2651..2687
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 2879..2900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2950..2979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3007..3035
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3019..3035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2601..2610
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2639..2648
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2677..2686
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP64080.1"
FT NON_TER 3109
FT /evidence="ECO:0000313|EMBL:KFP64080.1"
SQ SEQUENCE 3109 AA; 341569 MW; CF1DF68BEDAA2BC2 CRC64;
VLIKVLDNND NGPEFSHPSY DVTISEDILP DTEILQIEAI DRDEKHKLSY TIHSSIDTVS
MRKFRIDPST GVLYTAERLD HEAQDKHILN VMVRDQEFPY RRNLARVIIN VEDSNDHSPY
FTSPLYEASV FESAAVGSAV LQVTALDKDK GENAELIYTI EAGNTGNTFK IEPVLGIITL
LKEPDLTTMG QFVLSVKVTD QGSPPLSATA IVRISVTMAD NSHPKFTLKE YQAEVNENVD
IGTSVISLSA ISQSTLVYEI KDGNVDGVFT INPYSGVITS QKALDYERAS FYQLIVQATN
MAGMASNATV NIQIVDENDN PPVFLFSQYS GSISEAAPVN SIVRSTNNSP LVIRATDADS
NQNALLVYQI VESTAKKYFT VDSSTGAIRT IANLDHETIA HFHFHVHVRD SGNPQLTAES
PVEVTIEVTD VNDNPPVFSQ AVFETVLLLP TYVGVEVLKV KATDPDSEIP PELTYSLIEG
NMDHFLIDSS TGVLTIKNNS LSKDHYMLIV RVSDGKFYST AMVTIMVKEA MDSGLHFTQN
FYSTSISENS TNITKIAVVN AVGNRLNEPL KYSILNPGNK FKIKSTSGVI QTTGIPFDRE
EQELYELVVE ASRELDHLRV ARVVVRVYIE DINDNAPVFV GLPYYAAVQV DAEPGTLIYR
VTAIDKDKAE NGEVSYLLKE DYGHFEIDKG SGSVTLKEAF NSDLSNIEYL VVILAKDGGN
PSLSASVELP ITIVNKAMPV FDKPFYTASV NEDVEMHTPI LSINATSPEG QGIIYIIVDG
DPYNQFNIDF DTGVLSVISP LDYEINFLFK LMVRASDALT GARAEVTVDL IINDVNDNPP
VFDQSAYNAT LSEASLIGTP VLQVVAIDAD SDNNKIVQYQ IVQDTFNSTD YFHIDSTSGL
ILTARMLDHE LIQQCSLKVR ATDNGFPPLS SEVLVSISIT DMNDNPPVFN QLIYESYVSE
LAPRGHFVTC VQASDADSSD FDRLEYSILS GNDRTSFIMD SKSGVITLSN HRKQRMEPMY
SLNVSVSDGL FTSTAQVHIH ILGANLYSPV FSQSVYVAEV RENAAPGTKV IHVKATDGDS
GVYGQISYSV INDFAKDRFL IDSNGQILTT ERLDRENPLE SDIGIFLRAL DGGGRTTFCN
VRVIVVDEND NAPQFMTVEY RASVKADVGK GYLVTQVQAV DPDDGANSRI TYSLYSEASV
SVADLLEIDP DNGWMVTKGS FNQLKNTVLS FFVKAVDVPV KHSLIPVYIH VLPPETILPS
FSQPQYSFTI AEDTLIGSTI DILHILPNQG ALYSTVNGEL TENNKDGVFI IEQDTGLIKL
DKRLDHETNP AFHFKVAATI QLDKVDIVLT VDVEVKVLDV NDNKPMFETA SYDAIIMEGM
PIGTKLMQVK AVDADSSANG QVTYTLAVES ELEKITEAFT IDSNSGWIST LKDLDHEKDP
AFTFAVVASD LGEALSLSST TLVSVTVTDI NDNAPVFEHE VYRGSVKESD PPGEVVAVLS
TWDEDTSDVN RQVSYHITGG NPKGKFALGL VQNEWKVYVK RPLDREEQDV YYLNITATDG
LFVTQAAVEV TVTDVNDNNP VCEQVAYTAL FPEDIPSNKV ILKISAKDAD IGSNGEIRYS
LYGAGNNKFF LDPENGELKS LAPLDREKIP AYNLVARATD GGGRFCQSEI HLILEDVNDN
PPVFSSDHYT ACVYENTATK ALLTRVQATD PDVGVNRKVT YSLADSADGY FSVDRSSGII
ILEHPLDREL QSSYNISVKA SDQSIVLTLS SFATVTITVL DINDNPPVFE RRDYLVTVPE
DTSPGTEVLS VFATSQDIGT NAEIAYLIRS GNEKGKFRIN SKTGVISIFE ALDYESCKDF
YLVVEAKDGG TPALSAVTTV NVNVTDVNDN APKFSQVVYS AVISEDAAIG DSVIMLIAED
LDSPSNGQIH FSIVNGDQDN EFSIDPVLGL VKVKKKLDRE RISGYSLVIQ ARDSGTPPLS
SSVTVNVDIS DVNDNSPVFT PANYTAVIQE NKPVGTSILQ LVVTDKDSFH NGPPFTFTIL
TGNEEEEFTL DPHGVLRSAV IFKHMVATEY VLCVQAKDSG KPQQVSHTYV QVRVIEESIH
KPTAIPLEIF IVTMEDDFPG GVIGKIHATD QDVYDVLTYT LKSEQKSLFK VNSHDGKIIA
LGGLDNGKYV LNVSVSDGRF QVPIDVVVHV EQLLQEMLQN TVTIRFENVS PEDFVGLHMH
GFRRTLRNAV LSQKQDSLHI ISIQPVAGSN QLDMLFAVQM HNGGFYKPAY LIQKLTNARR
HLENVIRISA ILEKNCSGLD CQEQHCEQSL SIDSHSLMTY STARISFVCP RFYRNVRCMC
NGGLCPGSND PCLEKPCPGD MQCVGYEANR RPFICQCPPG KLGECSGHTS LSFAGNSYIK
YRVSENSKKE EFKLALRLRT LQSNGIIMYT RANPCIILKI VDGKLWFQLD CGSGPGILGI
SGRAVNDGSW HSVFLELNRN FTSLSLDDSY VERRKAPLYF QTLSTDSSVY FGAQVQVDNV
RSLTDKRTTQ VLSGFQGCLD SVVLNNNELP LQNKRSSFAE VVGLTELKLG CVLYPDACER
HPCQNGGTCT SVPSGGYQCN CLPQFTGRNC ESEITACFPN PCRNGGSCDP IGNAFICNCK
NGLTGVTCEE DINECEREEC ENGGSCVNIF GSFLCNCTPG YVGQYCGLRP VVVPNIQAGH
SYVGKEELIG IAVVLFVIFM LIVLFIIFRK KVFRKNYSRN NITLVQDPAT AALLNKSNGI
QFKNIRNSGD SRNIYQEVGP PQVPVRPMAY TPCFQSDSRN NLDKIVDGLG VEHQEMTTFH
PESPRILTAR RGVVVCSVAP NLPAVSPCRS DCDSIRKSTW DAGTESKGVD DAEEVTCFAG
SNKGSNSEVQ SLSSFQSDSG DDNAYHWDTS DWMPSARLSD IEEVPNFETA DGGSAHHGST
RELETDYYLG GYDIDSDYPP PHEEEFLSQD QLPPPLPEDY PDQYETLPPS QPVSMASTLS
PDCRRRPHFH PSQYLPPHQF PHETDTTGSQ SGNEFSTFAV GPSQNTENVS AGKMPLPLHN
SLDASSSDVS ASCGFDDSEV AMSDYESVEE LNLENVHIPF VETQHQTQV
//
