ID A0A091MV40_CARIC Unreviewed; 638 AA.
AC A0A091MV40;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
DE Flags: Fragment;
GN ORFNames=N322_02318 {ECO:0000313|EMBL:KFP65345.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP65345.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP65345.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP65345.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK517795; KFP65345.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091MV40; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR CDD; cd06658; STKc_PAK5; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR028754; STKc_PAK5.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF27; SERINE_THREONINE-PROTEIN KINASE PAK 5; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00285; PBD; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:KFP65345.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Transferase {ECO:0000313|EMBL:KFP65345.1}.
FT DOMAIN 8..21
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 368..619
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 93..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..271
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 398
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP65345.1"
FT NON_TER 638
FT /evidence="ECO:0000313|EMBL:KFP65345.1"
SQ SEQUENCE 638 AA; 72853 MW; 6188058F915C7795 CRC64;
KKKKRLEISG PSNFEHRVHT GFDHREQKFT GLPQQWHSLL ADTANRPKPM VDPSCITPIQ
LAPMKTIVRG NKPRKDTSIN GLLEEFDNIS VTRSNSLRKE SPPTHHQGNT NHVPRHQEEN
GYITYSQYSS ESDTTTDYVV EKYRDKSLYG EELDRYYKGS YAAKQNGHMM KVTSRDIYYS
EVTPLQSDLA RFLPDYHAHL ETKPKALEYG GLKLEYQRIP SGSSLDYRDP FPYTPSRASV
QSECPKERLE YSDGDWGHGL GKDDYDKRPK SSYVDPASPQ PAMRQRSSSY QYPLVYHKAS
HYHQPSLQPS SPYISTASYP SSPSITSSAY PPPSWGSSSD QQPSRVSHEQ FRAALQLVVS
PGDPREYLDN FIKIGEGSTG IVCIATEKHT GKQVAVKKMD LRKQQRRELL FNEVVIMRDY
HHENVVDMYN SYLVGDELWV VMEFLEGGAL TDIVTHTRMN EEQIATVCLS VLRALSYLHN
QGVIHRDIKS DSILLTSDGR IKLSDFGFCA QVSKEVPRRK SLVGTPYWMA PEEISRLPYG
TEVDIWSLGI MVIEMIDGEP PYFNEPPLQA MRRIRDNLPP RVKDMHKVSS VLRGFLDSML
VREPSQRATA QELLRHPFLK LAGPPSCIVP LMRQHRHR
//
