ID   A0A091NCI1_9PASS        Unreviewed;       602 AA.
AC   A0A091NCI1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=receptor protein-tyrosine kinase {ECO:0000256|ARBA:ARBA00011902};
DE            EC=2.7.10.1 {ECO:0000256|ARBA:ARBA00011902};
DE   Flags: Fragment;
GN   ORFNames=N310_13526 {ECO:0000313|EMBL:KFP87418.1};
OS   Acanthisitta chloris (rifleman).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC   Acanthisitta.
OX   NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP87418.1, ECO:0000313|Proteomes:UP000053537};
RN   [1] {ECO:0000313|EMBL:KFP87418.1, ECO:0000313|Proteomes:UP000053537}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP87418.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC         [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC         COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC         ChEBI:CHEBI:82620, ChEBI:CHEBI:456216; EC=2.7.10.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001171};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; KK845762; KFP87418.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091NCI1; -.
DR   Proteomes; UP000053537; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd00064; FU; 3.
DR   Gene3D; 3.80.20.20; Receptor L-domain; 2.
DR   InterPro; IPR006211; Furin-like_Cys-rich_dom.
DR   InterPro; IPR006212; Furin_repeat.
DR   InterPro; IPR032778; GF_recep_IV.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR000494; Rcpt_L-dom.
DR   InterPro; IPR036941; Rcpt_L-dom_sf.
DR   Pfam; PF00757; Furin-like; 1.
DR   Pfam; PF14843; GF_recep_IV; 1.
DR   Pfam; PF01030; Recep_L_domain; 2.
DR   SMART; SM00261; FU; 4.
DR   SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR   SUPFAM; SSF52058; L domain-like; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053537};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          28..139
FT                   /note="Receptor L-domain"
FT                   /evidence="ECO:0000259|Pfam:PF01030"
FT   DOMAIN          158..310
FT                   /note="Furin-like cysteine-rich"
FT                   /evidence="ECO:0000259|Pfam:PF00757"
FT   DOMAIN          333..451
FT                   /note="Receptor L-domain"
FT                   /evidence="ECO:0000259|Pfam:PF01030"
FT   DOMAIN          477..602
FT                   /note="Growth factor receptor"
FT                   /evidence="ECO:0000259|Pfam:PF14843"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP87418.1"
FT   NON_TER         602
FT                   /evidence="ECO:0000313|EMBL:KFP87418.1"
SQ   SEQUENCE   602 AA;  66656 MW;  D6819B9A2ACD1A92 CRC64;
     VCQGTNNKLT QLGHVEDHFT SLQRMYNNCE VVLSNLEITY VEHNRDLSFL KTIQEVAGYV
     LIALNMVDVI PLENLQIIRG NVLYDNSYAL AVLSNYHMNK TQGLRQLPMK RLSEILNGGV
     KISNNPKLCN MDTVLWNDII DKNKKPLTVL EFASNLSSCP KCHPNCTENH CWGPGESNCQ
     TLTKVICAQQ CSGRCRGKVP SDCCHNQCAA GCTGPRESDC LACRKFRDGT TCKDTCPPLV
     LYNPTTYQMD VNSEGKYSFG ATCVKECPHN YVVTDHGSCV RSCNANTYEV EENGVRKCKK
     CDGLCSKVCN GIGIGELKGI LSINATNIDS FKNCTKINGD VSILPVAFLG DAFTKTLPLD
     PKKLDVFKTV KEISGFLLIQ AWPENATDLY AFENLEIIRG RTKQHGQYSL AVVNLKIQSL
     GLRSLKEISD GDVAIMKNKN LCYADTMDWS NLFATQSQKT KILQNRDQNE CAAAKHVCDP
     LCSDVGCWGP GPFHCFSCRF FDRQKECVKQ CNILQGEPRE FEKDSKCLPC HPECLVQNST
     AYNATCTGPG PDNCMKCAHF IDGPHCVKSC PAGVLGENDT LVWKYADGNG VCQRCHPNCT
     RG
//