ID A0A091ND44_APAVI Unreviewed; 848 AA.
AC A0A091ND44;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Retinoblastoma-associated protein {ECO:0000313|EMBL:KFP87608.1};
DE Flags: Fragment;
GN ORFNames=N311_06035 {ECO:0000313|EMBL:KFP87608.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP87608.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP87608.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP87608.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC {ECO:0000256|ARBA:ARBA00009475}.
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DR EMBL; KL381529; KFP87608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091ND44; -.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0051172; P:negative regulation of nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20599; CYCLIN_RB; 1.
DR Gene3D; 1.10.472.140; -; 1.
DR Gene3D; 6.10.140.1380; -; 1.
DR Gene3D; 6.10.250.530; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR002720; RB_A.
DR InterPro; IPR002719; RB_B.
DR InterPro; IPR015030; RB_C.
DR InterPro; IPR028309; RB_fam.
DR InterPro; IPR024599; RB_N.
DR PANTHER; PTHR13742:SF17; RETINOBLASTOMA-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR Pfam; PF11934; DUF3452; 1.
DR Pfam; PF01858; RB_A; 1.
DR Pfam; PF01857; RB_B; 1.
DR Pfam; PF08934; Rb_C; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01367; DUF3452; 1.
DR SMART; SM01368; RB_A; 1.
DR SMART; SM01369; Rb_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..144
FT /note="Retinoblastoma-associated protein N-terminal"
FT /evidence="ECO:0000259|SMART:SM01367"
FT DOMAIN 290..492
FT /note="Retinoblastoma-associated protein A-box"
FT /evidence="ECO:0000259|SMART:SM01368"
FT DOMAIN 579..680
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 687..847
FT /note="Retinoblastoma-associated protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01369"
FT REGION 526..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 814..839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP87608.1"
FT NON_TER 848
FT /evidence="ECO:0000313|EMBL:KFP87608.1"
SQ SEQUENCE 848 AA; 97035 MW; D3D842FAD93F6BD3 CRC64;
YNKKQKETWG VCIFIVAIDL DEMTFTFTEL LKSISISVCK FFQFLKEVDV NMDTVSTKVD
STVSRLKKKY DVLLALYHKF ERTCGLIYLE QPSSEISAEL RSVLVLKNYW ITFLLAKGKV
LQVEDDLVIS FQLLLCVLDY FIKLSPPAML KEPYKSAVTA VSVNGSTRTP RRGQNRNTRT
SKPIDTDTKV IEVLCKEHDC NLDEVKNVYF TSFIPFLNSI GVVASNGLPE VEVLWKQYDE
LYLNNKDIDA RLFLDHDETL QPDVIKCSQL ERTPLKNNPD EELNHILPQT PVRAAMNNIQ
QLIMILNSAT DKPSDTLNMY FNNCTVNPTD SILKRVESFD DIFRKKFAEA VGQGCAEIGS
QRYKLGVRLY YRVMESMLKS EEERLSVQNF SKLLNDNIFH TSLLACAVEV VMATYGRNAS
QSDGTSAETD LSFPWILSVF ELKAFDIYKV IESFIKAEPS LTREMIKHLE RCEHRIMESL
AWQSGSPLFD LIKQSKEREG QTDQPEPTST LNLSLQHNHT AADLYLSPVR SPKKKGSGPS
VGATSAPDAQ PTATPQAQKL QKSTSLSLFY KKVYLLAYLR LRTLFFRLLP EHPDLEPLIW
TLFQHTLQNE YELMRDRHLD QIMMCSMYGI CKVKNIDLRF KTIVSAYKEL PNTNQETFKR
VLIREEQYDS IIVFYNLVFM QKLKTNILQY ASNRPPTLSP IPHIPRSPYQ FSNSPRRVPA
GNNIYISPLK SPYKFSDGFQ SPTKMTPRSR ILVSIGESFG TSEKFQKINQ MVGNSDCHLK
RSAEVSAAPK PLKRLRFDIE GQDEADGSKH LPQESKFQQK LAEMTSTRTR MQKQKLNDGN
DTSASEEK
//
