ID   A0A091P1Y9_HALAL        Unreviewed;       392 AA.
AC   A0A091P1Y9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=alpha-L-fucosidase {ECO:0000256|ARBA:ARBA00012662};
DE            EC=3.2.1.51 {ECO:0000256|ARBA:ARBA00012662};
DE   Flags: Fragment;
GN   ORFNames=N329_03640 {ECO:0000313|EMBL:KFQ02012.1};
OS   Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC   Accipitrinae; Haliaeetus.
OX   NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ02012.1, ECO:0000313|Proteomes:UP000054379};
RN   [1] {ECO:0000313|EMBL:KFQ02012.1, ECO:0000313|Proteomes:UP000054379}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ02012.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 29 family.
CC       {ECO:0000256|ARBA:ARBA00007951}.
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DR   EMBL; KK651559; KFQ02012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091P1Y9; -.
DR   Proteomes; UP000054379; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR031919; Fucosidase_C.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF45; PLASMA ALPHA-L-FUCOSIDASE; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   Pfam; PF16757; Fucosidase_C; 1.
DR   PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054379}.
FT   DOMAIN          301..388
FT                   /note="Alpha-L-fucosidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16757"
FT   SITE            219
FT                   /note="May be important for catalysis"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ02012.1"
FT   NON_TER         392
FT                   /evidence="ECO:0000313|EMBL:KFQ02012.1"
SQ   SEQUENCE   392 AA;  45095 MW;  6D18E761B0C7DCB0 CRC64;
     WYWQKEKRAP YVKFMEANYP PGFSYEDFGP LFTAEFFDPN QWADILKASG AKYVVLTSKH
     HEGFTLWGSK YSWNWNAVDV GPKRDLVAEL AMSVRNKTDL RFGLYHSLFE WFNPLFLEDA
     TNVFKTRKFP ASKSLPELYE IVTKYQPEII WSDGNGNAPD TYWNSTGFLA WLYNDSPVRD
     TVVTNDRWGV GSICTHGGFY TCSDRYNPGH FLPHKWENCM TIDKRSWGYR RNAQLDDYLT
     IEDLVKQLVE TVSCGGNLLM NIGPTHDGRI AVIFEERLRQ MGAWLKVNGE AIYGTKPWRA
     QNDTVTPEVW YTFSPKEGQV NAIFLNWPVS GTLELGEPQA KLGETQVKLV GYKELLKWVA
     LGEKGIVIAL PQLTPKQLPC QWGWTLQLID IN
//