ID A0A091P848_APAVI Unreviewed; 1296 AA.
AC A0A091P848;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 43.
DE SubName: Full=Son of sevenless 1 {ECO:0000313|EMBL:KFP87690.1};
DE Flags: Fragment;
GN ORFNames=N311_00762 {ECO:0000313|EMBL:KFP87690.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP87690.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP87690.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP87690.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL381637; KFP87690.1; -; Genomic_DNA.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd01261; PH_SOS; 1.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 6.10.250.3060; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF168; SON OF SEVENLESS HOMOLOG 1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244}.
FT DOMAIN 171..361
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 414..517
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 568..712
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 751..990
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 990..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1107..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1170..1184
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1219..1238
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1272..1287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP87690.1"
FT NON_TER 1296
FT /evidence="ECO:0000313|EMBL:KFP87690.1"
SQ SEQUENCE 1296 AA; 148715 MW; 251842DE245C42D0 CRC64;
VQVQVHPKLS STEDALQYVE ELILQLLNML CQAQPRSFLD VEDRVQKSFP HPIDKWAIAD
AQSAIEKRKR RNPLSLPVEK IHPLLKEVLG YKIDHQVSVY IVAVLEYISA DILKLVGNYV
RNIRHYEITK QDIKVAMCAD KVLMDMFHQD VEDLSALTLS DEEPSTSGEQ TYYDLVKSFM
AEVRQYIREL NLIIRVFREP YASNSKLFSS HDVENIFSRI SDIHELSVKL LGHIEDTVEM
TDEGSPHPLV GSCFEDMAEE LAFDPYESYA QDILRPGFHD HFLSQLSKPG AAFYLQSIGE
GFKEAVQYVL PRLLLAPVYH CLHYFELLKQ LEEKSEDEED KECLKQAITA LLNLQSSMER
ICSKSLAKRR LSESACRFYT QQMKGKQLAI KKMNEIQKNI DGWEGKDIGQ CCNEFIMEGT
LTRVGAKHER HIFLFDGLMI CCKSNHGQPR LPGASNAEYR LKEKFFMRKV QINDKDDTNE
YRHAFEIILK DENSVIFAAK SAEEKNNWMA ALISLQYRST LERMLDVTML QEEKEEQMRF
PNPELYRFAE PDSEENIVFE ENMQPKSGIP IIKAGTVIKL IERLTYHMYA DPNFVRTFLT
TYRSFCKPQE LLSLLIERFE IPEPEPTEAD RIAMENGDQP LSAELKRFRK EYIQPVQLRV
LNVCRHWVEH HFYDFERDAD LLQRLEEFIG TVRGKAMKKW VESITKIINR KKQAQAIGPS
HNITFESPPP AIEWHISKPG HTETFDLLTL HPIEIARQLT LLESDFYRAV QPSELVGSVW
TKEDKEINSP NLLKMIRHTT NLTLWFEKCI VETENLEERV IVVSRIIEIL QVFQELNNFN
GVLEIVSAMN SAAVYRLDHT FEQIPSRQKK ILEEAYELSE DHYKKYLAKL RSINPPCVPF
FGIYLTNILK TEEGNPEFLK RHGKELINFS KRRKVAEITG EIQQYQNQPY CLRVEFDIRR
FFENLNPMGN SMETEFTDYL FNKSLEIEPR NVKPPPRFPK KYSYPLKSPG VRPSNPRPGT
MRHPTPLQQE PRKISYSRIP ESETETTASA PNSPRTPLTP PPASATSSTT DACSVFDSDP
SSPFHASRIW FLCLLGSASV SSINFTKNSD EAHIPPPVPP RRRPESAPAE SSPSKITSAH
LDSPPAIPPR QPTSKVYSPR YSVPDRTCIS DPPESPPVLP PREPVRTPDV FSSSPLHLQP
PPLGRKSELG NTFFPNSPSL FTSPPPQTPS PHVARRHLPS PPLIPQDVDL HSVAGPPVPP
RQSTSQHIPK LPPKTYKREH THPSMHRDGP PLLENA
//
