ID A0A091P8S5_HALAL Unreviewed; 801 AA.
AC A0A091P8S5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Minor histocompatibility protein HA-1 {ECO:0000313|EMBL:KFQ03751.1};
DE Flags: Fragment;
GN ORFNames=N329_03243 {ECO:0000313|EMBL:KFQ03751.1};
OS Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Haliaeetus.
OX NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ03751.1, ECO:0000313|Proteomes:UP000054379};
RN [1] {ECO:0000313|EMBL:KFQ03751.1, ECO:0000313|Proteomes:UP000054379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ03751.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK654173; KFQ03751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091P8S5; -.
DR Proteomes; UP000054379; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20816; C1_GMIP-like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228:SF18; RHO GTPASE-ACTIVATING PROTEIN 45; 1.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU01077}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054379};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 151..356
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 524..569
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 583..800
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 105..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 198..232
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 259..304
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 110..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ03751.1"
FT NON_TER 801
FT /evidence="ECO:0000313|EMBL:KFQ03751.1"
SQ SEQUENCE 801 AA; 89368 MW; C9DA759597C0E36F CRC64;
GFCISSFPGF HYESNNETDK REFEKAVETI AVSFSSTVSE FLMGEVDSST ILSIPPSDQN
QTMESLYGGI PGPGGDGMPS GMENYDTGMG RFALKAHEVC RGSHTRHALS PALQPRTGQA
TPRGPSSLLQ PPSKRSLGSL VVRFLVSQTN MPFLSIYLLA LEQDMEHGTS VLQAANTLQH
QTFLQPLTVR RLEHEKRRKE IKEQWHRAQR KLQEAEVNLR KAKQIYMQRS EEHDKAKYMA
VKAEEEQQNT TSSITTKTLD KKRRLEEEAK NKAEEAMATY RTCVADANTQ KQELEDTKVN
SLRQIHEVIK QSDQVIKMIM HMQTAPLPVN FQTLCESSKL YDPGQQYASH VKQLQRGDEP
DIQFSSVLPS HPLRHSLFSF LPTRSPFTRT RKGSFNANDF STNAGSDGAG LPKDGTVSEG
GTGPKEQQSG AVAAERRGGR GHQVHKSWPT SITEADSSLD SNAGEFSHKL QRLSSNGTIS
SSEELEEKDE NATPFEQSIN GITPEMTAPT GPFRNVGLSK AAQTHRLRKL RTPSKCRECN
SYVYFQGAEC EECYLACHKK CLETLAIQCG HKKLQGKLQL FGQDFTKASQ SSSDGIPFII
KKCISEIEKR ALKTKGIYRV NGVKTRVEKL CQAFENGKEL VELSQASPHD ISNVLKLYLR
QLPEPIMPFR MYNELMGLAK ESLQGGEAKG KSGKGGPELV DRGAATDKVV VNLVLKLKEL
LKELPWENMA TLQYLLQHLR RIVEVEQDNK MTSSNLGIVF GPTLMRPRPT DATISLSSLV
DYPHQARIIE ALIIFYSTIF E
//
