ID A0A091PFZ1_HALAL Unreviewed; 315 AA.
AC A0A091PFZ1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
DE Flags: Fragment;
GN Name=Hs3st1_1 {ECO:0000313|EMBL:NWZ47246.1};
GN ORFNames=HALALB_R00798 {ECO:0000313|EMBL:NWZ47246.1}, N329_12082
GN {ECO:0000313|EMBL:KFQ06133.1};
OS Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Haliaeetus.
OX NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ06133.1, ECO:0000313|Proteomes:UP000054379};
RN [1] {ECO:0000313|EMBL:KFQ06133.1, ECO:0000313|Proteomes:UP000054379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ06133.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:NWZ47246.1, ECO:0000313|Proteomes:UP000585422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUT-0040 {ECO:0000313|EMBL:NWZ47246.1};
RC TISSUE=Blood {ECO:0000313|EMBL:NWZ47246.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|RuleBase:RU361155}.
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DR EMBL; KK657875; KFQ06133.1; -; Genomic_DNA.
DR EMBL; VZSQ01000012; NWZ47246.1; -; Genomic_DNA.
DR Proteomes; UP000054379; Unassembled WGS sequence.
DR Proteomes; UP000585422; Unassembled WGS sequence.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF16; HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000054379};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|RuleBase:RU361155, ECO:0000313|EMBL:KFQ06133.1}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..315
FT /note="Sulfotransferase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040562442"
FT DOMAIN 63..302
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT ACT_SITE 72
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 72..76
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 155
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 163
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 263
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 278..282
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 264..273
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
FT NON_TER 315
FT /evidence="ECO:0000313|EMBL:KFQ06133.1"
SQ SEQUENCE 315 AA; 37121 MW; B5D71ED5DDB742DC CRC64;
MAAFLLGAML LIVQPQIVPS RPAINSKAET SSQSVQRELL KKTSQKNDFK ENIHSNGSCR
QLPQTIIIGV RKGGTRALLE MLSLHPDIAA AESEVHFFDW EDHYKNGLQW YINQMPFSYP
HQITVEKTPA YFTSPKVPER VYNMNQSMRL LLILRDPSER VLSDYTQVFY NHMQKHKPYP
SIEQFLIKDG ELNVDYKAIN RSLYYIHMQN WLKYFPLDRI HIVDGDKLIK DPFPEIEKVE
RFLKLSPQIN ASNFYFNKTK GFYCLRDSGR ERCLHESKGR AHPQVDTRLL EKLHEYFHEP
NKKFFELVGR TFDWH
//
